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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNA2
All Species:
21.21
Human Site:
S143
Identified Species:
33.33
UniProt:
P51530
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51530
NP_001073918
1060
120415
S143
C
M
R
R
A
V
L
S
E
T
F
R
S
S
D
Chimpanzee
Pan troglodytes
XP_001163213
1147
129515
S230
C
M
R
R
A
V
L
S
E
T
F
R
S
S
D
Rhesus Macaque
Macaca mulatta
XP_001083328
329
36913
Dog
Lupus familis
XP_546133
1046
118517
S142
C
M
R
R
A
V
L
S
E
T
F
R
S
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQJ5
1062
119429
S144
C
L
R
R
A
V
L
S
E
T
F
R
G
S
D
Rat
Rattus norvegicus
XP_241671
1060
119682
S144
C
L
R
R
A
V
L
S
E
T
F
R
V
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520571
597
66551
Chicken
Gallus gallus
Q5ZKG3
992
111650
H133
T
L
V
G
T
I
L
H
E
I
F
Q
Q
S
V
Frog
Xenopus laevis
Q8QHA5
1053
119713
S149
C
L
R
R
S
V
L
S
E
K
F
K
V
C
D
Zebra Danio
Brachydanio rerio
XP_687974
1397
155209
K464
G
V
L
G
E
M
F
K
A
F
D
G
G
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727386
1100
124571
Q170
C
K
R
K
S
V
L
Q
E
R
F
R
G
L
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790939
971
108124
E29
V
D
E
D
N
L
L
E
E
V
G
E
Y
A
D
Poplar Tree
Populus trichocarpa
XP_002321254
1152
128362
E204
K
V
L
R
L
L
N
E
Q
S
G
E
E
R
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172361
1296
143231
V189
P
A
F
A
T
N
R
V
M
E
R
V
N
P
S
Baker's Yeast
Sacchar. cerevisiae
P38859
1522
171676
A252
E
K
K
A
E
V
N
A
E
E
V
D
K
M
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
29
84.1
N.A.
79.8
79.7
N.A.
44.7
62.2
62.5
45.2
N.A.
32.4
N.A.
N.A.
37.2
Protein Similarity:
100
92.1
29.8
90.1
N.A.
89.1
88.8
N.A.
50.7
76.5
77.5
58
N.A.
53.2
N.A.
N.A.
55.8
P-Site Identity:
100
100
0
100
N.A.
86.6
86.6
N.A.
0
26.6
60
6.6
N.A.
53.3
N.A.
N.A.
20
P-Site Similarity:
100
100
0
100
N.A.
93.3
93.3
N.A.
0
46.6
80
20
N.A.
66.6
N.A.
N.A.
33.3
Percent
Protein Identity:
27
N.A.
N.A.
27.5
24.8
N.A.
Protein Similarity:
44.7
N.A.
N.A.
43.8
41.5
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
6.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
14
34
0
0
7
7
0
0
0
0
7
0
% A
% Cys:
47
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
7
0
7
0
0
0
0
0
0
7
7
0
0
60
% D
% Glu:
7
0
7
0
14
0
0
14
67
14
0
14
7
0
0
% E
% Phe:
0
0
7
0
0
0
7
0
0
7
54
0
0
0
0
% F
% Gly:
7
0
0
14
0
0
0
0
0
0
14
7
20
0
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
0
7
0
0
0
0
0
% I
% Lys:
7
14
7
7
0
0
0
7
0
7
0
7
7
0
7
% K
% Leu:
0
27
14
0
7
14
60
0
0
0
0
0
0
7
0
% L
% Met:
0
20
0
0
0
7
0
0
7
0
0
0
0
7
0
% M
% Asn:
0
0
0
0
7
7
14
0
0
0
0
0
7
0
0
% N
% Pro:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
0
0
0
0
0
0
7
7
0
0
7
7
0
0
% Q
% Arg:
0
0
47
47
0
0
7
0
0
7
7
40
0
7
0
% R
% Ser:
0
0
0
0
14
0
0
40
0
7
0
0
20
47
7
% S
% Thr:
7
0
0
0
14
0
0
0
0
34
0
0
0
0
7
% T
% Val:
7
14
7
0
0
54
0
7
0
7
7
7
14
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _