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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNA2
All Species:
19.7
Human Site:
S173
Identified Species:
30.95
UniProt:
P51530
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51530
NP_001073918
1060
120415
S173
F
Q
K
A
I
N
N
S
F
A
P
E
K
L
Q
Chimpanzee
Pan troglodytes
XP_001163213
1147
129515
S260
F
Q
K
A
I
N
N
S
F
A
P
E
K
L
Q
Rhesus Macaque
Macaca mulatta
XP_001083328
329
36913
Dog
Lupus familis
XP_546133
1046
118517
S172
F
Q
K
A
I
S
N
S
F
A
P
E
K
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQJ5
1062
119429
S174
F
Q
K
A
I
S
E
S
F
A
P
E
R
L
Q
Rat
Rattus norvegicus
XP_241671
1060
119682
S174
F
Q
K
A
I
S
E
S
F
A
P
E
K
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520571
597
66551
Chicken
Gallus gallus
Q5ZKG3
992
111650
L163
I
V
Y
G
Q
K
Y
L
K
E
M
Y
H
L
K
Frog
Xenopus laevis
Q8QHA5
1053
119713
G179
F
Q
R
A
T
T
C
G
F
T
D
S
V
L
Q
Zebra Danio
Brachydanio rerio
XP_687974
1397
155209
S494
A
M
S
S
D
F
S
S
E
K
I
Q
T
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727386
1100
124571
K200
L
Q
K
V
L
R
Q
K
L
F
D
K
K
H
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790939
971
108124
P59
G
S
V
D
I
K
W
P
G
S
F
K
P
E
N
Poplar Tree
Populus trichocarpa
XP_002321254
1152
128362
E234
D
T
V
N
V
I
G
E
F
D
D
Q
G
K
C
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172361
1296
143231
S219
S
P
F
Q
T
P
P
S
L
S
C
P
H
N
K
Baker's Yeast
Sacchar. cerevisiae
P38859
1522
171676
K282
L
T
Q
K
Y
V
E
K
R
K
S
E
S
Q
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
29
84.1
N.A.
79.8
79.7
N.A.
44.7
62.2
62.5
45.2
N.A.
32.4
N.A.
N.A.
37.2
Protein Similarity:
100
92.1
29.8
90.1
N.A.
89.1
88.8
N.A.
50.7
76.5
77.5
58
N.A.
53.2
N.A.
N.A.
55.8
P-Site Identity:
100
100
0
93.3
N.A.
80
86.6
N.A.
0
6.6
40
6.6
N.A.
20
N.A.
N.A.
6.6
P-Site Similarity:
100
100
0
100
N.A.
93.3
93.3
N.A.
0
13.3
46.6
26.6
N.A.
33.3
N.A.
N.A.
20
Percent
Protein Identity:
27
N.A.
N.A.
27.5
24.8
N.A.
Protein Similarity:
44.7
N.A.
N.A.
43.8
41.5
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
40
0
0
0
0
0
34
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
7
% C
% Asp:
7
0
0
7
7
0
0
0
0
7
20
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
20
7
7
7
0
40
0
7
0
% E
% Phe:
40
0
7
0
0
7
0
0
47
7
7
0
0
7
0
% F
% Gly:
7
0
0
7
0
0
7
7
7
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
14
7
0
% H
% Ile:
7
0
0
0
40
7
0
0
0
0
7
0
0
0
14
% I
% Lys:
0
0
40
7
0
14
0
14
7
14
0
14
34
7
14
% K
% Leu:
14
0
0
0
7
0
0
7
14
0
0
0
0
47
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
7
0
14
20
0
0
0
0
0
0
7
7
% N
% Pro:
0
7
0
0
0
7
7
7
0
0
34
7
7
0
0
% P
% Gln:
0
47
7
7
7
0
7
0
0
0
0
14
0
7
40
% Q
% Arg:
0
0
7
0
0
7
0
0
7
0
0
0
7
0
0
% R
% Ser:
7
7
7
7
0
20
7
47
0
14
7
7
7
0
0
% S
% Thr:
0
14
0
0
14
7
0
0
0
7
0
0
7
0
0
% T
% Val:
0
7
14
7
7
7
0
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
0
7
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _