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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNA2
All Species:
17.58
Human Site:
S249
Identified Species:
27.62
UniProt:
P51530
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51530
NP_001073918
1060
120415
S249
S
D
N
S
K
D
N
S
T
C
N
I
E
V
V
Chimpanzee
Pan troglodytes
XP_001163213
1147
129515
S336
S
D
N
S
K
D
N
S
T
C
N
I
E
V
V
Rhesus Macaque
Macaca mulatta
XP_001083328
329
36913
Dog
Lupus familis
XP_546133
1046
118517
S248
S
D
G
N
N
N
N
S
T
C
N
I
E
V
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQJ5
1062
119429
S250
S
D
G
S
N
R
S
S
P
C
N
I
E
V
V
Rat
Rattus norvegicus
XP_241671
1060
119682
S250
S
D
S
S
D
R
S
S
P
C
N
I
E
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520571
597
66551
Chicken
Gallus gallus
Q5ZKG3
992
111650
G239
N
I
W
S
P
R
F
G
L
K
G
K
I
D
V
Frog
Xenopus laevis
Q8QHA5
1053
119713
K255
G
D
P
T
E
T
T
K
V
S
E
F
L
D
I
Zebra Danio
Brachydanio rerio
XP_687974
1397
155209
S570
A
L
S
K
Q
D
A
S
S
S
V
M
V
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727386
1100
124571
I276
Q
I
H
E
I
C
D
I
E
E
N
L
W
V
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790939
971
108124
L229
E
H
R
S
Q
L
I
L
Y
S
L
M
L
G
D
Poplar Tree
Populus trichocarpa
XP_002321254
1152
128362
N310
M
Q
D
N
P
T
I
N
F
L
E
E
Y
A
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172361
1296
143231
G295
V
D
C
A
V
D
E
G
P
V
S
L
P
K
M
Baker's Yeast
Sacchar. cerevisiae
P38859
1522
171676
E358
I
E
Y
N
S
S
D
E
F
S
D
D
S
L
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
29
84.1
N.A.
79.8
79.7
N.A.
44.7
62.2
62.5
45.2
N.A.
32.4
N.A.
N.A.
37.2
Protein Similarity:
100
92.1
29.8
90.1
N.A.
89.1
88.8
N.A.
50.7
76.5
77.5
58
N.A.
53.2
N.A.
N.A.
55.8
P-Site Identity:
100
100
0
66.6
N.A.
66.6
66.6
N.A.
0
13.3
6.6
13.3
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
0
86.6
N.A.
73.3
80
N.A.
0
20
26.6
46.6
N.A.
33.3
N.A.
N.A.
20
Percent
Protein Identity:
27
N.A.
N.A.
27.5
24.8
N.A.
Protein Similarity:
44.7
N.A.
N.A.
43.8
41.5
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
20
N.A.
N.A.
40
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
7
0
0
0
0
0
0
7
0
% A
% Cys:
0
0
7
0
0
7
0
0
0
34
0
0
0
0
0
% C
% Asp:
0
47
7
0
7
27
14
0
0
0
7
7
0
14
14
% D
% Glu:
7
7
0
7
7
0
7
7
7
7
14
7
34
0
0
% E
% Phe:
0
0
0
0
0
0
7
0
14
0
0
7
0
0
0
% F
% Gly:
7
0
14
0
0
0
0
14
0
0
7
0
0
7
0
% G
% His:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
14
0
0
7
0
14
7
0
0
0
34
7
0
20
% I
% Lys:
0
0
0
7
14
0
0
7
0
7
0
7
0
7
0
% K
% Leu:
0
7
0
0
0
7
0
7
7
7
7
14
14
7
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
14
0
0
7
% M
% Asn:
7
0
14
20
14
7
20
7
0
0
40
0
0
0
0
% N
% Pro:
0
0
7
0
14
0
0
0
20
0
0
0
7
0
7
% P
% Gln:
7
7
0
0
14
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
0
0
20
0
0
0
0
0
0
0
0
7
% R
% Ser:
34
0
14
40
7
7
14
40
7
27
7
0
7
0
0
% S
% Thr:
0
0
0
7
0
14
7
0
20
0
0
0
0
7
0
% T
% Val:
7
0
0
0
7
0
0
0
7
7
7
0
7
40
34
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
7
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _