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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNA2
All Species:
24.85
Human Site:
S470
Identified Species:
39.05
UniProt:
P51530
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51530
NP_001073918
1060
120415
S470
N
I
W
L
M
P
A
S
E
M
E
K
S
G
S
Chimpanzee
Pan troglodytes
XP_001163213
1147
129515
S557
N
I
W
L
M
P
A
S
E
M
E
K
S
G
S
Rhesus Macaque
Macaca mulatta
XP_001083328
329
36913
Dog
Lupus familis
XP_546133
1046
118517
S470
H
I
W
L
M
P
A
S
E
M
E
E
S
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQJ5
1062
119429
S471
S
I
W
L
T
P
A
S
E
L
E
E
S
G
N
Rat
Rattus norvegicus
XP_241671
1060
119682
S470
S
I
W
L
T
P
A
S
K
L
E
E
S
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520571
597
66551
L68
S
G
E
E
K
A
L
L
A
L
S
S
G
F
I
Chicken
Gallus gallus
Q5ZKG3
992
111650
I452
G
D
C
V
G
N
M
I
R
V
D
Q
V
Q
E
Frog
Xenopus laevis
Q8QHA5
1053
119713
S472
N
I
W
M
M
S
S
S
E
R
E
E
D
G
Q
Zebra Danio
Brachydanio rerio
XP_687974
1397
155209
Q788
N
I
W
L
Q
T
A
Q
Q
R
E
K
I
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727386
1100
124571
A489
E
R
E
K
E
G
I
A
I
R
H
L
K
L
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790939
971
108124
F442
E
A
S
L
D
K
C
F
M
K
G
G
D
R
V
Poplar Tree
Populus trichocarpa
XP_002321254
1152
128362
L558
R
I
W
R
P
H
S
L
K
S
D
R
S
T
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172361
1296
143231
S547
S
V
R
V
I
V
E
S
D
M
N
T
V
N
E
Baker's Yeast
Sacchar. cerevisiae
P38859
1522
171676
T845
L
F
L
L
D
G
S
T
R
E
S
R
S
G
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
29
84.1
N.A.
79.8
79.7
N.A.
44.7
62.2
62.5
45.2
N.A.
32.4
N.A.
N.A.
37.2
Protein Similarity:
100
92.1
29.8
90.1
N.A.
89.1
88.8
N.A.
50.7
76.5
77.5
58
N.A.
53.2
N.A.
N.A.
55.8
P-Site Identity:
100
100
0
86.6
N.A.
66.6
60
N.A.
0
0
53.3
53.3
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
0
100
N.A.
93.3
93.3
N.A.
13.3
26.6
73.3
60
N.A.
6.6
N.A.
N.A.
6.6
Percent
Protein Identity:
27
N.A.
N.A.
27.5
24.8
N.A.
Protein Similarity:
44.7
N.A.
N.A.
43.8
41.5
N.A.
P-Site Identity:
26.6
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
46.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
7
40
7
7
0
0
0
0
0
0
% A
% Cys:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
14
0
0
0
7
0
14
0
14
0
0
% D
% Glu:
14
0
14
7
7
0
7
0
34
7
47
27
0
0
14
% E
% Phe:
0
7
0
0
0
0
0
7
0
0
0
0
0
7
0
% F
% Gly:
7
7
0
0
7
14
0
0
0
0
7
7
7
54
7
% G
% His:
7
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
54
0
0
7
0
7
7
7
0
0
0
7
0
7
% I
% Lys:
0
0
0
7
7
7
0
0
14
7
0
20
7
0
0
% K
% Leu:
7
0
7
54
0
0
7
14
0
20
0
7
0
7
0
% L
% Met:
0
0
0
7
27
0
7
0
7
27
0
0
0
0
0
% M
% Asn:
27
0
0
0
0
7
0
0
0
0
7
0
0
7
14
% N
% Pro:
0
0
0
0
7
34
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
0
0
7
7
0
0
7
0
7
7
% Q
% Arg:
7
7
7
7
0
0
0
0
14
20
0
14
0
7
7
% R
% Ser:
27
0
7
0
0
7
20
47
0
7
14
7
47
0
27
% S
% Thr:
0
0
0
0
14
7
0
7
0
0
0
7
0
7
0
% T
% Val:
0
7
0
14
0
7
0
0
0
7
0
0
14
0
14
% V
% Trp:
0
0
54
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _