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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNA2
All Species:
32.73
Human Site:
S725
Identified Species:
51.43
UniProt:
P51530
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51530
NP_001073918
1060
120415
S725
C
R
S
K
S
I
K
S
L
A
L
L
E
E
L
Chimpanzee
Pan troglodytes
XP_001163213
1147
129515
S812
C
R
S
K
S
I
K
S
L
A
L
L
E
E
L
Rhesus Macaque
Macaca mulatta
XP_001083328
329
36913
P24
T
C
M
G
I
N
H
P
I
F
S
R
K
I
F
Dog
Lupus familis
XP_546133
1046
118517
S725
C
R
S
K
P
I
K
S
L
A
L
L
E
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQJ5
1062
119429
S726
C
R
S
R
S
I
A
S
L
A
H
L
E
E
L
Rat
Rattus norvegicus
XP_241671
1060
119682
S725
C
R
L
R
S
I
A
S
L
A
H
L
E
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520571
597
66551
T292
G
V
S
H
P
L
F
T
R
K
Q
F
D
F
C
Chicken
Gallus gallus
Q5ZKG3
992
111650
T682
H
P
D
I
R
K
F
T
E
E
E
I
C
R
S
Frog
Xenopus laevis
Q8QHA5
1053
119713
S726
C
K
A
K
S
I
K
S
L
S
A
L
E
E
L
Zebra Danio
Brachydanio rerio
XP_687974
1397
155209
T1042
C
R
A
K
G
I
Q
T
L
E
E
L
E
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727386
1100
124571
T734
R
L
T
K
D
C
K
T
V
E
E
L
E
K
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790939
971
108124
K666
I
F
H
C
S
S
Q
K
V
V
A
T
T
S
L
Poplar Tree
Populus trichocarpa
XP_002321254
1152
128362
S841
V
S
A
M
D
V
H
S
V
E
D
I
K
L
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172361
1296
143231
S983
F
S
A
M
N
M
C
S
V
E
D
I
K
K
K
Baker's Yeast
Sacchar. cerevisiae
P38859
1522
171676
N1149
Y
A
S
V
K
S
Y
N
D
Y
L
S
K
I
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
29
84.1
N.A.
79.8
79.7
N.A.
44.7
62.2
62.5
45.2
N.A.
32.4
N.A.
N.A.
37.2
Protein Similarity:
100
92.1
29.8
90.1
N.A.
89.1
88.8
N.A.
50.7
76.5
77.5
58
N.A.
53.2
N.A.
N.A.
55.8
P-Site Identity:
100
100
0
93.3
N.A.
80
73.3
N.A.
6.6
0
73.3
53.3
N.A.
26.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
13.3
93.3
N.A.
86.6
80
N.A.
26.6
13.3
93.3
80
N.A.
53.3
N.A.
N.A.
26.6
Percent
Protein Identity:
27
N.A.
N.A.
27.5
24.8
N.A.
Protein Similarity:
44.7
N.A.
N.A.
43.8
41.5
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
40
N.A.
N.A.
53.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
27
0
0
0
14
0
0
34
14
0
0
0
7
% A
% Cys:
47
7
0
7
0
7
7
0
0
0
0
0
7
0
7
% C
% Asp:
0
0
7
0
14
0
0
0
7
0
14
0
7
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
7
34
20
0
54
40
0
% E
% Phe:
7
7
0
0
0
0
14
0
0
7
0
7
0
7
7
% F
% Gly:
7
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% G
% His:
7
0
7
7
0
0
14
0
0
0
14
0
0
0
0
% H
% Ile:
7
0
0
7
7
47
0
0
7
0
0
20
0
14
0
% I
% Lys:
0
7
0
40
7
7
34
7
0
7
0
0
27
14
7
% K
% Leu:
0
7
7
0
0
7
0
0
47
0
27
54
0
7
54
% L
% Met:
0
0
7
14
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
7
0
7
0
0
0
0
0
0
7
% N
% Pro:
0
7
0
0
14
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
14
0
0
0
7
0
0
7
0
% Q
% Arg:
7
40
0
14
7
0
0
0
7
0
0
7
0
7
7
% R
% Ser:
0
14
40
0
40
14
0
54
0
7
7
7
0
7
7
% S
% Thr:
7
0
7
0
0
0
0
27
0
0
0
7
7
0
0
% T
% Val:
7
7
0
7
0
7
0
0
27
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _