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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNA2
All Species:
15.45
Human Site:
S818
Identified Species:
24.29
UniProt:
P51530
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51530
NP_001073918
1060
120415
S818
K
R
L
E
Q
N
K
S
A
V
V
Q
L
T
V
Chimpanzee
Pan troglodytes
XP_001163213
1147
129515
S905
K
R
L
E
Q
N
K
S
A
V
V
Q
L
T
V
Rhesus Macaque
Macaca mulatta
XP_001083328
329
36913
N105
L
T
V
Q
Y
R
M
N
S
K
I
M
S
L
S
Dog
Lupus familis
XP_546133
1046
118517
N818
K
R
L
E
Q
N
K
N
A
V
V
Q
L
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQJ5
1062
119429
S819
K
R
L
E
R
N
E
S
A
V
V
Q
L
T
V
Rat
Rattus norvegicus
XP_241671
1060
119682
S818
K
R
L
E
R
N
E
S
A
V
V
Q
L
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520571
597
66551
I373
Q
Y
R
M
N
S
K
I
M
S
L
S
N
K
L
Chicken
Gallus gallus
Q5ZKG3
992
111650
N766
Q
L
P
P
L
V
Q
N
S
E
A
R
D
L
G
Frog
Xenopus laevis
Q8QHA5
1053
119713
E819
K
R
L
E
R
N
Q
E
A
V
V
Q
L
T
V
Zebra Danio
Brachydanio rerio
XP_687974
1397
155209
D1135
K
R
L
E
H
H
R
D
A
V
V
Q
L
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727386
1100
124571
K826
F
Q
R
L
D
S
E
K
A
T
A
V
L
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790939
971
108124
T747
Q
R
L
V
S
A
H
T
S
S
V
T
S
L
S
Poplar Tree
Populus trichocarpa
XP_002321254
1152
128362
I923
A
R
E
N
G
M
G
I
S
L
F
C
R
L
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172361
1296
143231
I1065
A
R
E
N
G
M
G
I
S
L
F
R
R
L
S
Baker's Yeast
Sacchar. cerevisiae
P38859
1522
171676
E1243
T
F
C
E
K
H
P
E
S
V
A
E
L
T
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
29
84.1
N.A.
79.8
79.7
N.A.
44.7
62.2
62.5
45.2
N.A.
32.4
N.A.
N.A.
37.2
Protein Similarity:
100
92.1
29.8
90.1
N.A.
89.1
88.8
N.A.
50.7
76.5
77.5
58
N.A.
53.2
N.A.
N.A.
55.8
P-Site Identity:
100
100
0
93.3
N.A.
86.6
80
N.A.
6.6
0
80
66.6
N.A.
13.3
N.A.
N.A.
20
P-Site Similarity:
100
100
33.3
100
N.A.
100
100
N.A.
33.3
33.3
93.3
80
N.A.
46.6
N.A.
N.A.
40
Percent
Protein Identity:
27
N.A.
N.A.
27.5
24.8
N.A.
Protein Similarity:
44.7
N.A.
N.A.
43.8
41.5
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
26.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
0
0
7
0
0
54
0
20
0
0
0
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
7
0
0
0
0
7
0
0
% D
% Glu:
0
0
14
54
0
0
20
14
0
7
0
7
0
0
0
% E
% Phe:
7
7
0
0
0
0
0
0
0
0
14
0
0
0
0
% F
% Gly:
0
0
0
0
14
0
14
0
0
0
0
0
0
0
7
% G
% His:
0
0
0
0
7
14
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
20
0
0
7
0
0
0
7
% I
% Lys:
47
0
0
0
7
0
27
7
0
7
0
0
0
7
0
% K
% Leu:
7
7
54
7
7
0
0
0
0
14
7
0
60
34
20
% L
% Met:
0
0
0
7
0
14
7
0
7
0
0
7
0
0
0
% M
% Asn:
0
0
0
14
7
40
0
20
0
0
0
0
7
7
0
% N
% Pro:
0
0
7
7
0
0
7
0
0
0
0
0
0
0
0
% P
% Gln:
20
7
0
7
20
0
14
0
0
0
0
47
0
0
0
% Q
% Arg:
0
67
14
0
20
7
7
0
0
0
0
14
14
0
0
% R
% Ser:
0
0
0
0
7
14
0
27
40
14
0
7
14
7
27
% S
% Thr:
7
7
0
0
0
0
0
7
0
7
0
7
0
47
0
% T
% Val:
0
0
7
7
0
7
0
0
0
54
54
7
0
0
40
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _