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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNA2
All Species:
17.88
Human Site:
T449
Identified Species:
28.1
UniProt:
P51530
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51530
NP_001073918
1060
120415
T449
S
L
W
C
L
M
L
T
L
E
S
Q
S
K
D
Chimpanzee
Pan troglodytes
XP_001163213
1147
129515
T536
S
L
W
C
L
M
L
T
L
E
S
Q
S
K
D
Rhesus Macaque
Macaca mulatta
XP_001083328
329
36913
Dog
Lupus familis
XP_546133
1046
118517
T449
S
L
W
C
L
M
L
T
L
E
S
Q
S
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQJ5
1062
119429
T450
S
L
W
C
L
M
L
T
L
E
S
Q
S
K
D
Rat
Rattus norvegicus
XP_241671
1060
119682
L450
L
W
C
L
M
L
T
L
E
S
Q
S
K
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520571
597
66551
P48
Q
R
K
N
G
T
L
P
K
T
N
L
M
V
G
Chicken
Gallus gallus
Q5ZKG3
992
111650
N432
D
S
K
K
G
Y
K
N
I
W
M
I
P
S
L
Frog
Xenopus laevis
Q8QHA5
1053
119713
T451
R
L
W
Y
L
M
C
T
L
E
A
N
S
K
D
Zebra Danio
Brachydanio rerio
XP_687974
1397
155209
L768
H
W
L
L
L
C
S
L
E
A
L
T
M
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727386
1100
124571
S469
E
E
Q
H
N
R
Q
S
S
H
V
R
S
F
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790939
971
108124
L422
Q
Q
S
G
G
F
T
L
V
F
R
R
K
Q
G
Poplar Tree
Populus trichocarpa
XP_002321254
1152
128362
G504
P
P
M
L
Q
V
H
G
G
S
K
E
S
S
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172361
1296
143231
V514
S
T
I
G
K
K
A
V
K
V
S
E
V
I
D
Baker's Yeast
Sacchar. cerevisiae
P38859
1522
171676
F612
I
L
Y
F
V
N
K
F
V
S
K
S
N
Y
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
29
84.1
N.A.
79.8
79.7
N.A.
44.7
62.2
62.5
45.2
N.A.
32.4
N.A.
N.A.
37.2
Protein Similarity:
100
92.1
29.8
90.1
N.A.
89.1
88.8
N.A.
50.7
76.5
77.5
58
N.A.
53.2
N.A.
N.A.
55.8
P-Site Identity:
100
100
0
100
N.A.
100
0
N.A.
6.6
0
66.6
6.6
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
0
100
N.A.
100
13.3
N.A.
13.3
6.6
73.3
20
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
27
N.A.
N.A.
27.5
24.8
N.A.
Protein Similarity:
44.7
N.A.
N.A.
43.8
41.5
N.A.
P-Site Identity:
6.6
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
0
0
7
7
0
0
0
0
% A
% Cys:
0
0
7
27
0
7
7
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
40
% D
% Glu:
7
7
0
0
0
0
0
0
14
34
0
14
0
7
0
% E
% Phe:
0
0
0
7
0
7
0
7
0
7
0
0
0
7
0
% F
% Gly:
0
0
0
14
20
0
0
7
7
0
0
0
0
0
27
% G
% His:
7
0
0
7
0
0
7
0
0
7
0
0
0
0
0
% H
% Ile:
7
0
7
0
0
0
0
0
7
0
0
7
0
7
0
% I
% Lys:
0
0
14
7
7
7
14
0
14
0
14
0
14
34
0
% K
% Leu:
7
40
7
20
40
7
34
20
34
0
7
7
0
0
7
% L
% Met:
0
0
7
0
7
34
0
0
0
0
7
0
14
0
0
% M
% Asn:
0
0
0
7
7
7
0
7
0
0
7
7
7
0
7
% N
% Pro:
7
7
0
0
0
0
0
7
0
0
0
0
7
0
0
% P
% Gln:
14
7
7
0
7
0
7
0
0
0
7
27
0
7
0
% Q
% Arg:
7
7
0
0
0
7
0
0
0
0
7
14
0
0
0
% R
% Ser:
34
7
7
0
0
0
7
7
7
20
34
14
47
14
0
% S
% Thr:
0
7
0
0
0
7
14
34
0
7
0
7
0
0
7
% T
% Val:
0
0
0
0
7
7
0
7
14
7
7
0
7
7
0
% V
% Trp:
0
14
34
0
0
0
0
0
0
7
0
0
0
0
7
% W
% Tyr:
0
0
7
7
0
7
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _