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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNA2
All Species:
24.55
Human Site:
T585
Identified Species:
38.57
UniProt:
P51530
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51530
NP_001073918
1060
120415
T585
L
S
K
L
M
E
N
T
F
V
S
K
K
L
R
Chimpanzee
Pan troglodytes
XP_001163213
1147
129515
T672
L
S
K
L
M
E
N
T
F
V
S
K
K
L
R
Rhesus Macaque
Macaca mulatta
XP_001083328
329
36913
Dog
Lupus familis
XP_546133
1046
118517
T585
L
S
K
L
M
E
N
T
C
V
S
Q
K
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQJ5
1062
119429
T586
L
S
K
L
M
E
S
T
D
P
S
K
R
L
R
Rat
Rattus norvegicus
XP_241671
1060
119682
T585
L
S
K
L
M
E
N
T
D
S
S
K
R
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520571
597
66551
L179
Q
A
M
K
H
V
L
L
S
K
D
Y
T
L
I
Chicken
Gallus gallus
Q5ZKG3
992
111650
L563
V
S
E
K
L
R
N
L
I
I
D
F
H
K
P
Frog
Xenopus laevis
Q8QHA5
1053
119713
S586
L
S
R
L
M
E
N
S
S
V
S
E
K
L
R
Zebra Danio
Brachydanio rerio
XP_687974
1397
155209
T903
L
S
M
L
M
E
N
T
P
T
S
E
R
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727386
1100
124571
G600
L
G
M
L
L
S
E
G
E
R
F
Q
E
L
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790939
971
108124
D553
Q
V
A
T
I
M
R
D
L
N
E
D
Q
R
A
Poplar Tree
Populus trichocarpa
XP_002321254
1152
128362
E688
V
W
Q
I
D
K
D
E
F
M
T
S
F
S
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172361
1296
143231
H698
L
L
R
K
D
I
A
H
P
H
G
S
K
G
S
Baker's Yeast
Sacchar. cerevisiae
P38859
1522
171676
L965
S
L
I
A
T
Q
N
L
V
T
Y
R
I
D
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
29
84.1
N.A.
79.8
79.7
N.A.
44.7
62.2
62.5
45.2
N.A.
32.4
N.A.
N.A.
37.2
Protein Similarity:
100
92.1
29.8
90.1
N.A.
89.1
88.8
N.A.
50.7
76.5
77.5
58
N.A.
53.2
N.A.
N.A.
55.8
P-Site Identity:
100
100
0
86.6
N.A.
73.3
80
N.A.
6.6
13.3
73.3
66.6
N.A.
26.6
N.A.
N.A.
0
P-Site Similarity:
100
100
0
93.3
N.A.
86.6
86.6
N.A.
13.3
40
93.3
80
N.A.
46.6
N.A.
N.A.
13.3
Percent
Protein Identity:
27
N.A.
N.A.
27.5
24.8
N.A.
Protein Similarity:
44.7
N.A.
N.A.
43.8
41.5
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
7
0
0
7
0
0
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
14
0
7
7
14
0
14
7
0
7
0
% D
% Glu:
0
0
7
0
0
47
7
7
7
0
7
14
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
20
0
7
7
7
0
0
% F
% Gly:
0
7
0
0
0
0
0
7
0
0
7
0
0
7
0
% G
% His:
0
0
0
0
7
0
0
7
0
7
0
0
7
0
0
% H
% Ile:
0
0
7
7
7
7
0
0
7
7
0
0
7
0
7
% I
% Lys:
0
0
34
20
0
7
0
0
0
7
0
27
34
7
7
% K
% Leu:
60
14
0
54
14
0
7
20
7
0
0
0
0
60
0
% L
% Met:
0
0
20
0
47
7
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
54
0
0
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
14
7
0
0
0
0
7
% P
% Gln:
14
0
7
0
0
7
0
0
0
0
0
14
7
0
0
% Q
% Arg:
0
0
14
0
0
7
7
0
0
7
0
7
20
7
54
% R
% Ser:
7
54
0
0
0
7
7
7
14
7
47
14
0
7
7
% S
% Thr:
0
0
0
7
7
0
0
40
0
14
7
0
7
0
0
% T
% Val:
14
7
0
0
0
7
0
0
7
27
0
0
0
0
7
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _