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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNA2
All Species:
20
Human Site:
Y496
Identified Species:
31.43
UniProt:
P51530
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51530
NP_001073918
1060
120415
Y496
K
I
V
C
D
G
Q
Y
L
H
N
F
Q
C
K
Chimpanzee
Pan troglodytes
XP_001163213
1147
129515
Y583
K
I
V
C
D
G
Q
Y
L
H
N
F
Q
C
K
Rhesus Macaque
Macaca mulatta
XP_001083328
329
36913
Dog
Lupus familis
XP_546133
1046
118517
Y496
K
T
I
C
D
G
Q
Y
L
H
N
F
Q
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQJ5
1062
119429
Y497
S
R
V
C
D
G
Q
Y
L
H
N
F
Q
R
K
Rat
Rattus norvegicus
XP_241671
1060
119682
Y496
K
R
V
C
D
G
H
Y
L
H
N
F
Q
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520571
597
66551
N90
V
T
C
I
L
D
R
N
L
S
K
L
P
G
N
Chicken
Gallus gallus
Q5ZKG3
992
111650
G474
H
S
F
Q
R
K
N
G
A
V
P
G
A
N
L
Frog
Xenopus laevis
Q8QHA5
1053
119713
Q497
V
Q
T
I
S
D
V
Q
Y
L
H
S
F
Q
R
Zebra Danio
Brachydanio rerio
XP_687974
1397
155209
Y814
S
I
L
S
D
G
V
Y
K
H
S
F
E
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727386
1100
124571
T511
E
E
G
R
Y
R
Q
T
L
E
L
G
E
E
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790939
971
108124
G464
R
R
V
A
L
C
V
G
F
I
E
T
I
S
K
Poplar Tree
Populus trichocarpa
XP_002321254
1152
128362
P599
R
F
V
H
K
K
M
P
L
H
D
V
H
A
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172361
1296
143231
G609
L
Q
S
D
Q
T
Q
G
I
S
V
Q
R
S
D
Baker's Yeast
Sacchar. cerevisiae
P38859
1522
171676
F876
E
G
A
Y
I
Y
C
F
S
R
R
R
N
D
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
29
84.1
N.A.
79.8
79.7
N.A.
44.7
62.2
62.5
45.2
N.A.
32.4
N.A.
N.A.
37.2
Protein Similarity:
100
92.1
29.8
90.1
N.A.
89.1
88.8
N.A.
50.7
76.5
77.5
58
N.A.
53.2
N.A.
N.A.
55.8
P-Site Identity:
100
100
0
80
N.A.
80
80
N.A.
6.6
0
0
46.6
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
100
0
86.6
N.A.
80
80
N.A.
13.3
0
13.3
66.6
N.A.
26.6
N.A.
N.A.
20
Percent
Protein Identity:
27
N.A.
N.A.
27.5
24.8
N.A.
Protein Similarity:
44.7
N.A.
N.A.
43.8
41.5
N.A.
P-Site Identity:
20
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
0
0
0
0
7
0
0
0
7
7
7
% A
% Cys:
0
0
7
34
0
7
7
0
0
0
0
0
0
14
0
% C
% Asp:
0
0
0
7
40
14
0
0
0
0
7
0
0
7
7
% D
% Glu:
14
7
0
0
0
0
0
0
0
7
7
0
14
7
0
% E
% Phe:
0
7
7
0
0
0
0
7
7
0
0
40
7
0
0
% F
% Gly:
0
7
7
0
0
40
0
20
0
0
0
14
0
7
0
% G
% His:
7
0
0
7
0
0
7
0
0
47
7
0
7
0
0
% H
% Ile:
0
20
7
14
7
0
0
0
7
7
0
0
7
0
0
% I
% Lys:
27
0
0
0
7
14
0
0
7
0
7
0
0
0
47
% K
% Leu:
7
0
7
0
14
0
0
0
54
7
7
7
0
0
7
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
7
0
0
34
0
7
7
14
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
7
0
7
0
0
% P
% Gln:
0
14
0
7
7
0
40
7
0
0
0
7
34
7
0
% Q
% Arg:
14
20
0
7
7
7
7
0
0
7
7
7
7
27
7
% R
% Ser:
14
7
7
7
7
0
0
0
7
14
7
7
0
14
7
% S
% Thr:
0
14
7
0
0
7
0
7
0
0
0
7
0
0
0
% T
% Val:
14
0
40
0
0
0
20
0
0
7
7
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
7
7
0
40
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _