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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDH3G
All Species:
23.94
Human Site:
T247
Identified Species:
47.88
UniProt:
P51553
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51553
NP_004126.1
393
42794
T247
A
A
R
Y
P
Q
I
T
F
E
N
M
I
V
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70404
393
42767
T247
A
A
H
Y
P
Q
I
T
F
D
S
M
I
V
D
Rat
Rattus norvegicus
P41565
393
42833
T247
A
A
R
Y
P
Q
I
T
F
D
S
M
I
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511168
376
41276
T230
A
A
R
Y
P
N
I
T
F
E
N
M
I
V
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086122
391
42851
T245
A
S
G
Y
P
D
I
T
F
E
S
M
I
V
D
Zebra Danio
Brachydanio rerio
XP_699839
289
31870
D164
V
S
K
P
Y
Q
F
D
V
M
V
M
P
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VWH4
377
40826
Q242
A
Q
K
F
P
E
I
Q
F
E
E
K
Y
L
D
Honey Bee
Apis mellifera
XP_393876
384
42391
T244
A
K
D
Y
P
D
I
T
H
N
D
M
I
I
D
Nematode Worm
Caenorhab. elegans
Q93353
379
41534
Q241
A
K
Q
Y
P
K
I
Q
F
E
S
M
I
I
D
Sea Urchin
Strong. purpuratus
XP_001175786
362
39467
E218
A
A
R
Y
P
E
I
E
F
N
D
L
I
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q945K7
374
40606
T238
A
E
K
Y
P
E
I
T
Y
E
E
V
V
I
D
Baker's Yeast
Sacchar. cerevisiae
P28834
360
39306
D221
Q
K
E
Y
P
D
I
D
V
S
S
I
I
V
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
95.1
95.6
N.A.
88.8
N.A.
77.8
56.7
N.A.
40.9
53.6
47.5
60
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
97.1
97.9
N.A.
92.3
N.A.
85.7
64.6
N.A.
60.3
68.9
65.3
73.7
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
80
86.6
N.A.
93.3
N.A.
73.3
13.3
N.A.
40
53.3
60
66.6
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
93.3
100
N.A.
93.3
N.A.
86.6
26.6
N.A.
66.6
66.6
86.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
44
45.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.8
63.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
84
42
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
25
0
17
0
17
17
0
0
0
92
% D
% Glu:
0
9
9
0
0
25
0
9
0
50
17
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
9
0
67
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
92
0
0
0
0
9
75
25
0
% I
% Lys:
0
25
25
0
0
9
0
0
0
0
0
9
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
67
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
17
17
0
0
9
0
% N
% Pro:
0
0
0
9
92
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
9
9
9
0
0
34
0
17
0
0
0
0
0
0
0
% Q
% Arg:
0
0
34
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
17
0
0
0
0
0
0
0
9
42
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
59
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
0
0
0
0
17
0
9
9
9
59
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
84
9
0
0
0
9
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _