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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDH3G
All Species:
27.88
Human Site:
Y344
Identified Species:
55.76
UniProt:
P51553
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51553
NP_004126.1
393
42794
Y344
D
H
L
K
L
H
S
Y
A
T
S
I
R
K
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70404
393
42767
Y344
D
H
L
K
L
H
S
Y
A
T
S
I
R
K
A
Rat
Rattus norvegicus
P41565
393
42833
Y344
D
H
L
K
L
H
S
Y
A
T
S
I
R
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511168
376
41276
Y327
D
H
L
K
L
H
T
Y
A
A
S
I
R
K
A
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086122
391
42851
Y342
D
H
L
K
L
H
S
Y
A
A
S
I
R
K
A
Zebra Danio
Brachydanio rerio
XP_699839
289
31870
N253
S
A
I
L
T
T
M
N
E
T
R
L
H
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VWH4
377
40826
Y338
R
H
M
E
L
N
T
Y
A
D
K
I
E
R
A
Honey Bee
Apis mellifera
XP_393876
384
42391
H341
R
H
L
G
H
K
D
H
A
T
L
I
Q
N
A
Nematode Worm
Caenorhab. elegans
Q93353
379
41534
W338
N
H
L
H
L
D
A
W
G
N
S
L
R
Q
A
Sea Urchin
Strong. purpuratus
XP_001175786
362
39467
Y315
D
H
L
G
L
D
S
Y
A
K
A
I
R
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q945K7
374
40606
Q335
R
H
L
K
F
N
E
Q
A
E
Q
I
H
S
A
Baker's Yeast
Sacchar. cerevisiae
P28834
360
39306
Y318
N
H
L
G
L
N
E
Y
A
T
R
I
S
K
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
95.1
95.6
N.A.
88.8
N.A.
77.8
56.7
N.A.
40.9
53.6
47.5
60
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
97.1
97.9
N.A.
92.3
N.A.
85.7
64.6
N.A.
60.3
68.9
65.3
73.7
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
86.6
N.A.
93.3
6.6
N.A.
40
40
40
66.6
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
93.3
N.A.
93.3
20
N.A.
73.3
53.3
73.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
44
45.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.8
63.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
9
0
84
17
9
0
0
0
92
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
0
0
0
0
17
9
0
0
9
0
0
0
0
0
% D
% Glu:
0
0
0
9
0
0
17
0
9
9
0
0
9
0
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
25
0
0
0
0
9
0
0
0
0
0
0
% G
% His:
0
92
0
9
9
42
0
9
0
0
0
0
17
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
84
0
0
0
% I
% Lys:
0
0
0
50
0
9
0
0
0
9
9
0
0
50
0
% K
% Leu:
0
0
84
9
75
0
0
0
0
0
9
17
0
0
0
% L
% Met:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
17
0
0
0
0
25
0
9
0
9
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
9
0
9
9
0
% Q
% Arg:
25
0
0
0
0
0
0
0
0
0
17
0
59
17
0
% R
% Ser:
9
0
0
0
0
0
42
0
0
0
50
0
9
9
0
% S
% Thr:
0
0
0
0
9
9
17
0
0
50
0
0
0
9
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _