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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
P2RX1
All Species:
20.91
Human Site:
T386
Identified Species:
46
UniProt:
P51575
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51575
NP_002549.1
399
44980
T386
A
E
R
D
L
A
A
T
S
S
T
L
G
L
Q
Chimpanzee
Pan troglodytes
XP_511276
399
44988
T386
A
E
R
D
L
A
A
T
S
S
T
L
G
L
Q
Rhesus Macaque
Macaca mulatta
XP_001092205
399
44921
T386
D
E
R
D
L
A
A
T
G
S
T
L
G
L
Q
Dog
Lupus familis
XP_548344
399
44773
T386
G
E
H
D
P
A
A
T
S
S
T
L
G
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
P51576
399
44832
T386
G
E
R
D
P
A
A
T
S
S
T
L
G
L
Q
Rat
Rattus norvegicus
P47824
399
44938
T386
G
E
H
D
P
V
A
T
S
S
T
L
G
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517186
376
41501
L363
D
L
L
L
L
H
I
L
P
K
R
H
Y
Y
K
Chicken
Gallus gallus
NP_989850
392
44493
K380
Y
A
E
Q
E
P
S
K
S
N
K
K
E
K
E
Frog
Xenopus laevis
NP_001082067
391
44317
Y379
K
Y
K
Y
V
E
D
Y
D
E
L
V
G
S
E
Zebra Danio
Brachydanio rerio
NP_945333
398
45110
L386
I
C
E
E
T
P
A
L
P
Q
T
Q
E
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792184
418
46849
D405
K
K
F
Q
L
V
D
D
I
P
Y
E
D
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.4
90.7
N.A.
89.4
88.9
N.A.
45.8
66.4
50.8
52.6
N.A.
N.A.
N.A.
N.A.
40.4
Protein Similarity:
100
100
99.2
96.2
N.A.
94.2
93.4
N.A.
56.6
79.6
71.9
69.4
N.A.
N.A.
N.A.
N.A.
61.2
P-Site Identity:
100
100
86.6
80
N.A.
86.6
73.3
N.A.
6.6
6.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
86.6
80
N.A.
86.6
73.3
N.A.
13.3
26.6
33.3
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
0
0
0
46
64
0
0
0
0
0
0
10
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
0
55
0
0
19
10
10
0
0
0
10
10
10
% D
% Glu:
0
55
19
10
10
10
0
0
0
10
0
10
19
0
19
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
28
0
0
0
0
0
0
0
10
0
0
0
64
0
0
% G
% His:
0
0
19
0
0
10
0
0
0
0
0
10
0
0
0
% H
% Ile:
10
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% I
% Lys:
19
10
10
0
0
0
0
10
0
10
10
10
0
10
10
% K
% Leu:
0
10
10
10
46
0
0
19
0
0
10
55
0
55
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
28
19
0
0
19
10
0
0
0
0
0
% P
% Gln:
0
0
0
19
0
0
0
0
0
10
0
10
0
0
55
% Q
% Arg:
0
0
37
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
0
55
55
0
0
0
10
10
% S
% Thr:
0
0
0
0
10
0
0
55
0
0
64
0
0
0
0
% T
% Val:
0
0
0
0
10
19
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
0
10
0
0
0
10
0
0
10
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _