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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
P2RY4
All Species:
14.24
Human Site:
S238
Identified Species:
34.81
UniProt:
P51582
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51582
NP_002556.1
365
40963
S238
L
P
G
S
A
Q
S
S
S
R
L
R
S
L
R
Chimpanzee
Pan troglodytes
XP_529029
292
32805
R172
S
S
R
L
R
S
L
R
T
I
A
V
V
L
T
Rhesus Macaque
Macaca mulatta
XP_001083871
365
41047
S238
L
P
G
A
A
Q
S
S
S
R
L
R
S
L
R
Dog
Lupus familis
XP_542321
377
42380
L236
A
Y
G
A
S
G
G
L
P
R
A
K
R
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJS7
361
41016
S234
L
P
G
A
G
Q
S
S
S
R
L
R
S
L
R
Rat
Rattus norvegicus
O35811
361
40875
S234
L
P
G
A
G
Q
S
S
S
R
L
R
S
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518271
346
38599
I211
F
A
G
P
F
L
T
I
L
A
C
Y
A
L
M
Chicken
Gallus gallus
P34996
362
41176
P242
Y
K
D
L
D
N
S
P
L
R
R
K
S
I
Y
Frog
Xenopus laevis
P79928
537
62006
T246
I
V
S
G
N
Q
Q
T
L
P
S
Y
K
K
R
Zebra Danio
Brachydanio rerio
B0UXR0
366
40819
G232
N
Q
L
T
E
R
S
G
K
T
K
K
A
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.4
96.9
51.7
N.A.
80.5
82.4
N.A.
52.8
37.8
39.1
28.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
79.7
98
64.7
N.A.
86.5
88.4
N.A.
67.1
55.3
50.8
47.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
13.3
N.A.
86.6
86.6
N.A.
13.3
20
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
33.3
N.A.
93.3
93.3
N.A.
26.6
33.3
26.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
40
20
0
0
0
0
10
20
0
20
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
60
10
20
10
10
10
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
10
0
10
0
0
0
10
0
% I
% Lys:
0
10
0
0
0
0
0
0
10
0
10
30
10
20
0
% K
% Leu:
40
0
10
20
0
10
10
10
30
0
40
0
0
60
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
10
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
40
0
10
0
0
0
10
10
10
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
50
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
10
10
0
10
0
60
10
40
10
10
50
% R
% Ser:
10
10
10
10
10
10
60
40
40
0
10
0
50
0
10
% S
% Thr:
0
0
0
10
0
0
10
10
10
10
0
0
0
0
10
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
0
0
0
0
0
0
0
0
0
20
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _