Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRCA2 All Species: 8.48
Human Site: S1632 Identified Species: 26.67
UniProt: P51587 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51587 NP_000050.2 3418 384225 S1632 E N L K T S K S I F L K V K V
Chimpanzee Pan troglodytes XP_509619 3418 384101 S1632 E N L K T S K S I F L K V K V
Rhesus Macaque Macaca mulatta XP_001118184 3359 377526 S1616 T S C S R K R S V S Q T S L L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P97929 3329 370645 N1605 V Q E N I E N N V E K N P R I
Rat Rattus norvegicus O35923 3343 372198 S1606 R Q T E N L T S N G S S P K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510808 3547 393173 L1758 L C N Q T I A L K T P S T V P
Chicken Gallus gallus NP_989607 3397 377697 V1609 K V G A F I N V D E D C E R N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001103864 2874 317397 S1195 T N A L I S N S K S V T F S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 91.1 N.A. N.A. 57 56.7 N.A. 40.9 33.9 N.A. 26.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 94 N.A. N.A. 70.8 70.7 N.A. 57.8 52.5 N.A. 44.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 N.A. N.A. 0 20 N.A. 6.6 0 N.A. 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 33.3 N.A. N.A. 26.6 26.6 N.A. 13.3 13.3 N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 13 0 0 13 0 0 0 0 0 0 0 0 % A
% Cys: 0 13 13 0 0 0 0 0 0 0 0 13 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 13 0 13 0 0 0 13 % D
% Glu: 25 0 13 13 0 13 0 0 0 25 0 0 13 0 0 % E
% Phe: 0 0 0 0 13 0 0 0 0 25 0 0 13 0 0 % F
% Gly: 0 0 13 0 0 0 0 0 0 13 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 25 25 0 0 25 0 0 0 0 0 13 % I
% Lys: 13 0 0 25 0 13 25 0 25 0 13 25 0 38 0 % K
% Leu: 13 0 25 13 0 13 0 13 0 0 25 0 0 13 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 38 13 13 13 0 38 13 13 0 0 13 0 0 13 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 13 0 25 0 13 % P
% Gln: 0 25 0 13 0 0 0 0 0 0 13 0 0 0 0 % Q
% Arg: 13 0 0 0 13 0 13 0 0 0 0 0 0 25 0 % R
% Ser: 0 13 0 13 0 38 0 63 0 25 13 25 13 13 0 % S
% Thr: 25 0 13 0 38 0 13 0 0 13 0 25 13 0 0 % T
% Val: 13 13 0 0 0 0 0 13 25 0 13 0 25 13 38 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _