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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRCA2
All Species:
6.36
Human Site:
T1815
Identified Species:
20
UniProt:
P51587
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51587
NP_000050.2
3418
384225
T1815
I
C
V
E
E
L
V
T
S
S
S
P
C
K
N
Chimpanzee
Pan troglodytes
XP_509619
3418
384101
T1815
I
C
V
E
E
L
V
T
S
S
S
P
C
K
N
Rhesus Macaque
Macaca mulatta
XP_001118184
3359
377526
H1792
G
K
I
I
C
V
S
H
E
T
I
K
K
V
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P97929
3329
370645
K1781
I
N
E
Y
C
V
Q
K
L
E
T
N
T
S
P
Rat
Rattus norvegicus
O35923
3343
372198
K1783
I
S
A
T
K
E
I
K
L
H
P
Q
T
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510808
3547
393173
L1938
K
G
S
T
D
S
Q
L
A
F
H
N
L
T
D
Chicken
Gallus gallus
NP_989607
3397
377697
S1788
L
T
C
L
Q
E
T
S
L
N
A
E
S
Q
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103864
2874
317397
A1371
G
N
V
G
F
S
T
A
G
G
R
K
M
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
91.1
N.A.
N.A.
57
56.7
N.A.
40.9
33.9
N.A.
26.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
94
N.A.
N.A.
70.8
70.7
N.A.
57.8
52.5
N.A.
44.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
N.A.
N.A.
6.6
13.3
N.A.
0
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
N.A.
N.A.
20
26.6
N.A.
20
40
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
0
0
0
13
13
0
13
0
0
0
0
% A
% Cys:
0
25
13
0
25
0
0
0
0
0
0
0
25
0
0
% C
% Asp:
0
0
0
0
13
0
0
0
0
0
0
0
0
13
13
% D
% Glu:
0
0
13
25
25
25
0
0
13
13
0
13
0
0
0
% E
% Phe:
0
0
0
0
13
0
0
0
0
13
0
0
0
0
0
% F
% Gly:
25
13
0
13
0
0
0
0
13
13
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
13
0
13
13
0
0
0
0
% H
% Ile:
50
0
13
13
0
0
13
0
0
0
13
0
0
0
13
% I
% Lys:
13
13
0
0
13
0
0
25
0
0
0
25
13
25
25
% K
% Leu:
13
0
0
13
0
25
0
13
38
0
0
0
13
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% M
% Asn:
0
25
0
0
0
0
0
0
0
13
0
25
0
0
38
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
13
25
0
0
13
% P
% Gln:
0
0
0
0
13
0
25
0
0
0
0
13
0
13
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% R
% Ser:
0
13
13
0
0
25
13
13
25
25
25
0
13
13
0
% S
% Thr:
0
13
0
25
0
0
25
25
0
13
13
0
25
13
0
% T
% Val:
0
0
38
0
0
25
25
0
0
0
0
0
0
25
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _