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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HCFC1 All Species: 2.12
Human Site: S1205 Identified Species: 4.24
UniProt: P51610 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51610 NP_005325.2 2035 208732 S1205 A R E P G G R S P A F V Q L A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001088011 1702 173511 G900 S T S L A G A G G H S T S A S
Dog Lupus familis XP_867443 2039 208943 T1208 V E S G G R G T T F V Q L A P
Cat Felis silvestris
Mouse Mus musculus Q61191 2045 210519 S1214 F V Q L A L P S V R V G L S G
Rat Rattus norvegicus Q5RKG2 723 79130
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509058 2033 207643 A1188 P P A Q R G E A G L P G S P G
Chicken Gallus gallus XP_001234928 787 86020
Frog Xenopus laevis NP_001087989 2101 219049 S1232 S F T S G L T S S N L P C E T
Zebra Danio Brachydanio rerio Q7ZUV7 1173 122182 R371 A V K V A S T R L P S P K A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V4C8 1500 160166 L698 F I Q K P L T L A P N V Q L Q
Honey Bee Apis mellifera XP_624189 1550 166762 V748 Q G V K M I V V S S G A M G G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791039 1216 126587 P414 S T K P L Q S P I K A Q A P G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 82.3 93.8 N.A. 93.7 24.2 N.A. 82.4 26.3 68.8 20.4 N.A. 33 34.2 N.A. 37
Protein Similarity: 100 N.A. 82.5 95 N.A. 95.5 30 N.A. 86 32.2 76.6 33.1 N.A. 47.5 50.2 N.A. 46.5
P-Site Identity: 100 N.A. 6.6 6.6 N.A. 6.6 0 N.A. 6.6 0 13.3 6.6 N.A. 20 0 N.A. 6.6
P-Site Similarity: 100 N.A. 20 13.3 N.A. 13.3 0 N.A. 13.3 0 20 20 N.A. 26.6 6.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 9 0 25 0 9 9 9 9 9 9 9 25 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 9 0 0 0 9 0 0 0 0 0 0 9 0 % E
% Phe: 17 9 0 0 0 0 0 0 0 9 9 0 0 0 0 % F
% Gly: 0 9 0 9 25 25 9 9 17 0 9 17 0 9 34 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 9 0 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 17 17 0 0 0 0 0 9 0 0 9 0 0 % K
% Leu: 0 0 0 17 9 25 0 9 9 9 9 0 17 17 9 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 9 9 0 0 0 0 % N
% Pro: 9 9 0 17 9 0 9 9 9 17 9 17 0 17 9 % P
% Gln: 9 0 17 9 0 9 0 0 0 0 0 17 17 0 9 % Q
% Arg: 0 9 0 0 9 9 9 9 0 9 0 0 0 0 0 % R
% Ser: 25 0 17 9 0 9 9 25 17 9 17 0 17 9 9 % S
% Thr: 0 17 9 0 0 0 25 9 9 0 0 9 0 0 9 % T
% Val: 9 17 9 9 0 0 9 9 9 0 17 17 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _