KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCFC1
All Species:
3.03
Human Site:
S1246
Identified Species:
6.06
UniProt:
P51610
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51610
NP_005325.2
2035
208732
S1246
T
A
A
M
T
R
S
S
V
G
A
G
E
P
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088011
1702
173511
T941
S
A
A
Q
T
T
L
T
A
A
G
G
L
T
T
Dog
Lupus familis
XP_867443
2039
208943
M1249
P
T
T
V
R
S
T
M
G
S
G
E
P
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61191
2045
210519
E1255
R
S
I
M
V
A
G
E
L
G
A
A
R
V
V
Rat
Rattus norvegicus
Q5RKG2
723
79130
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509058
2033
207643
G1229
A
R
S
N
M
G
A
G
E
P
D
G
V
R
A
Chicken
Gallus gallus
XP_001234928
787
86020
G26
P
V
P
R
S
R
H
G
H
R
A
V
A
I
R
Frog
Xenopus laevis
NP_001087989
2101
219049
E1273
V
C
S
D
P
R
S
E
T
Y
E
T
G
T
I
Zebra Danio
Brachydanio rerio
Q7ZUV7
1173
122182
Q412
Q
G
S
I
S
T
A
Q
S
T
A
L
A
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4C8
1500
160166
P739
H
G
I
S
I
A
N
P
H
L
A
S
G
I
T
Honey Bee
Apis mellifera
XP_624189
1550
166762
N789
G
S
P
Q
A
I
F
N
P
G
K
S
Q
I
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791039
1216
126587
T455
P
G
V
Q
Q
Q
N
T
L
S
G
I
V
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
82.3
93.8
N.A.
93.7
24.2
N.A.
82.4
26.3
68.8
20.4
N.A.
33
34.2
N.A.
37
Protein Similarity:
100
N.A.
82.5
95
N.A.
95.5
30
N.A.
86
32.2
76.6
33.1
N.A.
47.5
50.2
N.A.
46.5
P-Site Identity:
100
N.A.
26.6
0
N.A.
20
0
N.A.
6.6
20
13.3
6.6
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
N.A.
40
13.3
N.A.
33.3
0
N.A.
20
26.6
20
33.3
N.A.
13.3
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
17
0
9
17
17
0
9
9
42
9
17
17
17
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
17
9
0
9
9
9
0
9
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
9
25
0
0
0
9
9
17
9
25
25
25
17
0
0
% G
% His:
9
0
0
0
0
0
9
0
17
0
0
0
0
0
0
% H
% Ile:
0
0
17
9
9
9
0
0
0
0
0
9
0
25
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
9
0
17
9
0
9
9
0
9
% L
% Met:
0
0
0
17
9
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
17
9
0
0
0
0
0
0
0
% N
% Pro:
25
0
17
0
9
0
0
9
9
9
0
0
9
9
0
% P
% Gln:
9
0
0
25
9
9
0
9
0
0
0
0
9
0
0
% Q
% Arg:
9
9
0
9
9
25
0
0
0
9
0
0
9
9
17
% R
% Ser:
9
17
25
9
17
9
17
9
9
17
0
17
0
9
0
% S
% Thr:
9
9
9
0
17
17
9
17
9
9
0
9
0
17
17
% T
% Val:
9
9
9
9
9
0
0
0
9
0
0
9
17
9
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _