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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCFC1
All Species:
12.42
Human Site:
T1844
Identified Species:
24.85
UniProt:
P51610
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51610
NP_005325.2
2035
208732
T1844
P
S
D
D
D
L
G
T
V
P
D
Y
N
Q
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088011
1702
173511
Q1514
Q
V
S
P
G
P
R
Q
Q
L
P
P
R
Q
L
Dog
Lupus familis
XP_867443
2039
208943
T1848
P
S
D
D
D
S
G
T
V
P
D
Y
N
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61191
2045
210519
T1854
Q
S
D
D
D
S
G
T
V
P
D
Y
N
Q
L
Rat
Rattus norvegicus
Q5RKG2
723
79130
F535
Q
W
C
D
V
G
I
F
K
N
N
T
A
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509058
2033
207643
T1843
P
T
D
D
D
S
G
T
I
P
D
Y
N
Q
L
Chicken
Gallus gallus
XP_001234928
787
86020
F599
Q
W
Y
D
V
G
I
F
K
N
S
S
A
V
V
Frog
Xenopus laevis
NP_001087989
2101
219049
V1911
V
N
D
D
D
S
V
V
L
P
D
Y
S
Q
L
Zebra Danio
Brachydanio rerio
Q7ZUV7
1173
122182
H985
P
P
P
L
Q
A
H
H
P
V
G
S
S
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4C8
1500
160166
G1312
P
R
T
N
L
E
P
G
T
A
Y
R
F
R
L
Honey Bee
Apis mellifera
XP_624189
1550
166762
I1362
V
P
L
E
Q
G
T
I
Y
K
L
R
I
A
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791039
1216
126587
K1028
G
Q
A
I
Q
L
A
K
K
D
V
N
Q
W
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
82.3
93.8
N.A.
93.7
24.2
N.A.
82.4
26.3
68.8
20.4
N.A.
33
34.2
N.A.
37
Protein Similarity:
100
N.A.
82.5
95
N.A.
95.5
30
N.A.
86
32.2
76.6
33.1
N.A.
47.5
50.2
N.A.
46.5
P-Site Identity:
100
N.A.
13.3
93.3
N.A.
86.6
6.6
N.A.
80
6.6
53.3
6.6
N.A.
13.3
0
N.A.
6.6
P-Site Similarity:
100
N.A.
13.3
93.3
N.A.
86.6
20
N.A.
93.3
13.3
73.3
20
N.A.
26.6
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
9
9
0
0
9
0
0
17
9
9
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
42
59
42
0
0
0
0
9
42
0
0
0
0
% D
% Glu:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
17
0
0
0
0
9
0
0
% F
% Gly:
9
0
0
0
9
25
34
9
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
17
9
9
0
0
0
9
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
25
9
0
0
0
9
0
% K
% Leu:
0
0
9
9
9
17
0
0
9
9
9
0
0
9
59
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
9
0
0
0
0
0
17
9
9
34
0
0
% N
% Pro:
42
17
9
9
0
9
9
0
9
42
9
9
0
0
0
% P
% Gln:
34
9
0
0
25
0
0
9
9
0
0
0
9
50
0
% Q
% Arg:
0
9
0
0
0
0
9
0
0
0
0
17
9
9
0
% R
% Ser:
0
25
9
0
0
34
0
0
0
0
9
17
17
0
0
% S
% Thr:
0
9
9
0
0
0
9
34
9
0
0
9
0
0
9
% T
% Val:
17
9
0
0
17
0
9
9
25
9
9
0
0
9
17
% V
% Trp:
0
17
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
9
0
0
0
0
0
9
0
9
42
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _