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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH5A1
All Species:
25.15
Human Site:
S285
Identified Species:
50.3
UniProt:
P51649
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51649
NP_001071.1
535
57215
S285
S
K
I
S
F
T
G
S
T
T
T
G
K
I
L
Chimpanzee
Pan troglodytes
Q6A2H0
535
57110
S285
S
K
I
S
F
T
G
S
T
T
T
G
K
I
L
Rhesus Macaque
Macaca mulatta
XP_001101142
535
56988
S285
S
K
I
S
F
T
G
S
T
T
T
G
K
I
L
Dog
Lupus familis
XP_545368
482
51416
D269
V
F
D
S
A
N
V
D
Q
A
V
A
G
A
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWF0
523
55950
S273
S
K
I
S
F
T
G
S
T
A
T
G
K
I
L
Rat
Rattus norvegicus
P51650
523
56113
S273
S
K
I
S
F
T
G
S
T
A
T
G
K
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418909
548
57904
S298
A
K
I
S
F
T
G
S
T
A
T
G
K
I
L
Frog
Xenopus laevis
Q6GNL7
902
99964
I654
G
F
T
G
S
T
P
I
G
K
Q
I
M
K
S
Zebra Danio
Brachydanio rerio
XP_002664997
514
55133
V280
L
R
H
A
A
G
T
V
K
R
V
S
M
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789239
489
52301
N272
N
A
P
F
I
V
F
N
S
A
D
V
D
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SAK4
528
56541
S276
R
K
I
T
F
T
G
S
T
A
V
G
K
K
L
Baker's Yeast
Sacchar. cerevisiae
P38067
497
54171
P270
F
E
L
G
G
N
A
P
F
I
V
F
E
D
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.4
76.4
N.A.
83.9
84.6
N.A.
N.A.
72.6
24.1
68.2
N.A.
N.A.
N.A.
N.A.
55.1
Protein Similarity:
100
99.6
97.5
81.8
N.A.
88.4
89.3
N.A.
N.A.
81.9
36.8
80.7
N.A.
N.A.
N.A.
N.A.
70.4
P-Site Identity:
100
100
100
6.6
N.A.
93.3
93.3
N.A.
N.A.
86.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
13.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
6.6
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.1
44.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
71.2
60.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
9
17
0
9
0
0
50
0
9
0
17
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
9
0
0
9
0
9
9
0
% D
% Glu:
0
9
0
0
0
0
0
0
0
0
0
0
9
9
0
% E
% Phe:
9
17
0
9
59
0
9
0
9
0
0
9
0
0
0
% F
% Gly:
9
0
0
17
9
9
59
0
9
0
0
59
9
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
59
0
9
0
0
9
0
9
0
9
0
50
0
% I
% Lys:
0
59
0
0
0
0
0
0
9
9
0
0
59
17
0
% K
% Leu:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
9
% M
% Asn:
9
0
0
0
0
17
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
9
9
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% Q
% Arg:
9
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
42
0
0
59
9
0
0
59
9
0
0
9
0
0
9
% S
% Thr:
0
0
9
9
0
67
9
0
59
25
50
0
0
0
0
% T
% Val:
9
0
0
0
0
9
9
9
0
0
34
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _