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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH5A1
All Species:
26.97
Human Site:
S299
Identified Species:
53.94
UniProt:
P51649
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51649
NP_001071.1
535
57215
S299
L
L
H
H
A
A
N
S
V
K
R
V
S
M
E
Chimpanzee
Pan troglodytes
Q6A2H0
535
57110
S299
L
L
H
H
A
A
N
S
V
K
R
V
S
M
E
Rhesus Macaque
Macaca mulatta
XP_001101142
535
56988
S299
L
L
H
H
A
A
N
S
V
K
R
V
S
M
E
Dog
Lupus familis
XP_545368
482
51416
S283
M
A
S
K
F
R
N
S
G
Q
T
C
V
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWF0
523
55950
S287
L
L
H
H
A
A
N
S
V
K
R
V
S
M
E
Rat
Rattus norvegicus
P51650
523
56113
S287
L
L
H
H
A
A
N
S
V
K
R
V
S
M
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418909
548
57904
T312
L
L
K
H
A
A
G
T
V
K
R
V
S
M
E
Frog
Xenopus laevis
Q6GNL7
902
99964
K668
S
C
A
V
S
N
V
K
K
V
S
L
E
L
G
Zebra Danio
Brachydanio rerio
XP_002664997
514
55133
I294
L
G
G
H
A
P
F
I
V
F
D
S
A
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789239
489
52301
C286
A
V
S
G
A
M
V
C
K
F
R
G
S
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SAK4
528
56541
T290
L
M
A
A
A
A
P
T
V
K
K
V
S
L
E
Baker's Yeast
Sacchar. cerevisiae
P38067
497
54171
E284
A
D
L
D
Q
A
L
E
Q
A
M
A
C
K
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.4
76.4
N.A.
83.9
84.6
N.A.
N.A.
72.6
24.1
68.2
N.A.
N.A.
N.A.
N.A.
55.1
Protein Similarity:
100
99.6
97.5
81.8
N.A.
88.4
89.3
N.A.
N.A.
81.9
36.8
80.7
N.A.
N.A.
N.A.
N.A.
70.4
P-Site Identity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
80
0
26.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
N.A.
86.6
20
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.1
44.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
71.2
60.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
17
9
75
67
0
0
0
9
0
9
9
0
0
% A
% Cys:
0
9
0
0
0
0
0
9
0
0
0
9
9
9
0
% C
% Asp:
0
9
0
9
0
0
0
0
0
0
9
0
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
59
% E
% Phe:
0
0
0
0
9
0
9
0
0
17
0
0
0
0
9
% F
% Gly:
0
9
9
9
0
0
9
0
9
0
0
9
0
9
9
% G
% His:
0
0
42
59
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
9
0
0
0
9
17
59
9
0
0
9
0
% K
% Leu:
67
50
9
0
0
0
9
0
0
0
0
9
0
17
0
% L
% Met:
9
9
0
0
0
9
0
0
0
0
9
0
0
50
0
% M
% Asn:
0
0
0
0
0
9
50
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
9
9
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
9
0
0
0
0
59
0
0
0
0
% R
% Ser:
9
0
17
0
9
0
0
50
0
0
9
9
67
0
9
% S
% Thr:
0
0
0
0
0
0
0
17
0
0
9
0
0
0
0
% T
% Val:
0
9
0
9
0
0
17
0
67
9
0
59
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _