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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH5A1
All Species:
22.12
Human Site:
S331
Identified Species:
44.24
UniProt:
P51649
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51649
NP_001071.1
535
57215
S331
A
V
A
G
A
M
A
S
K
F
R
N
T
G
Q
Chimpanzee
Pan troglodytes
Q6A2H0
535
57110
S331
A
V
A
G
A
M
A
S
K
F
R
N
T
G
Q
Rhesus Macaque
Macaca mulatta
XP_001101142
535
56988
S331
A
V
A
G
A
L
A
S
K
F
R
N
T
G
Q
Dog
Lupus familis
XP_545368
482
51416
L315
A
E
A
M
K
T
N
L
R
V
G
N
G
F
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWF0
523
55950
S319
A
V
A
G
A
M
A
S
K
F
R
N
A
G
Q
Rat
Rattus norvegicus
P51650
523
56113
S319
A
V
A
G
A
M
A
S
K
F
R
N
A
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418909
548
57904
S344
A
V
A
G
A
L
A
S
K
Y
R
N
S
G
Q
Frog
Xenopus laevis
Q6GNL7
902
99964
F700
R
M
G
M
S
S
V
F
F
N
K
G
E
N
C
Zebra Danio
Brachydanio rerio
XP_002664997
514
55133
F326
T
C
V
C
S
N
R
F
L
V
Q
T
G
I
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789239
489
52301
E318
F
C
Q
K
M
A
A
E
V
E
K
L
V
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SAK4
528
56541
A322
A
V
K
G
T
L
A
A
K
F
R
N
S
G
Q
Baker's Yeast
Sacchar. cerevisiae
P38067
497
54171
K316
S
I
I
D
K
F
A
K
L
L
A
E
R
V
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.4
76.4
N.A.
83.9
84.6
N.A.
N.A.
72.6
24.1
68.2
N.A.
N.A.
N.A.
N.A.
55.1
Protein Similarity:
100
99.6
97.5
81.8
N.A.
88.4
89.3
N.A.
N.A.
81.9
36.8
80.7
N.A.
N.A.
N.A.
N.A.
70.4
P-Site Identity:
100
100
93.3
20
N.A.
93.3
93.3
N.A.
N.A.
80
0
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
33.3
N.A.
93.3
93.3
N.A.
N.A.
100
20
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.1
44.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
71.2
60.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
0
59
0
50
9
75
9
0
0
9
0
17
0
0
% A
% Cys:
0
17
0
9
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
0
0
9
0
9
0
9
9
0
9
% E
% Phe:
9
0
0
0
0
9
0
17
9
50
0
0
0
9
0
% F
% Gly:
0
0
9
59
0
0
0
0
0
0
9
9
17
59
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
9
9
0
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
9
9
17
0
0
9
59
0
17
0
0
0
9
% K
% Leu:
0
0
0
0
0
25
0
9
17
9
0
9
0
0
0
% L
% Met:
0
9
0
17
9
34
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
9
0
0
9
0
67
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
59
% Q
% Arg:
9
0
0
0
0
0
9
0
9
0
59
0
9
0
0
% R
% Ser:
9
0
0
0
17
9
0
50
0
0
0
0
17
0
0
% S
% Thr:
9
0
0
0
9
9
0
0
0
0
0
9
25
0
0
% T
% Val:
0
59
9
0
0
0
9
0
9
17
0
0
9
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _