KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH5A1
All Species:
10.91
Human Site:
S63
Identified Species:
21.82
UniProt:
P51649
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51649
NP_001071.1
535
57215
S63
A
A
L
L
R
T
D
S
F
V
G
G
R
W
L
Chimpanzee
Pan troglodytes
Q6A2H0
535
57110
S63
A
A
L
L
R
T
D
S
F
V
G
G
R
W
L
Rhesus Macaque
Macaca mulatta
XP_001101142
535
56988
S63
A
A
L
L
R
T
D
S
F
V
G
G
R
W
L
Dog
Lupus familis
XP_545368
482
51416
L61
G
S
G
S
P
S
Q
L
K
I
F
N
E
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWF0
523
55950
T63
R
W
L
P
A
P
A
T
F
P
V
Y
D
P
A
Rat
Rattus norvegicus
P51650
523
56113
T63
R
W
L
P
T
P
A
T
F
P
V
Y
D
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418909
548
57904
A76
A
A
L
V
R
R
G
A
L
V
G
G
R
W
V
Frog
Xenopus laevis
Q6GNL7
902
99964
W331
S
E
E
I
R
A
A
W
R
R
I
L
T
N
V
Zebra Danio
Brachydanio rerio
XP_002664997
514
55133
A62
S
F
P
V
F
D
P
A
T
G
E
E
I
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789239
489
52301
D61
E
A
I
K
V
A
N
D
T
F
Y
G
P
W
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SAK4
528
56541
D63
L
I
G
G
K
W
L
D
S
Y
D
N
K
T
I
Baker's Yeast
Sacchar. cerevisiae
P38067
497
54171
D62
S
V
V
E
E
A
I
D
V
A
Y
E
T
F
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.4
76.4
N.A.
83.9
84.6
N.A.
N.A.
72.6
24.1
68.2
N.A.
N.A.
N.A.
N.A.
55.1
Protein Similarity:
100
99.6
97.5
81.8
N.A.
88.4
89.3
N.A.
N.A.
81.9
36.8
80.7
N.A.
N.A.
N.A.
N.A.
70.4
P-Site Identity:
100
100
100
0
N.A.
13.3
13.3
N.A.
N.A.
60
6.6
0
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
20
N.A.
20
20
N.A.
N.A.
80
26.6
20
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.1
44.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
71.2
60.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
42
0
0
9
25
25
17
0
9
0
0
0
9
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
25
25
0
0
9
0
17
0
0
% D
% Glu:
9
9
9
9
9
0
0
0
0
0
9
17
9
0
0
% E
% Phe:
0
9
0
0
9
0
0
0
42
9
9
0
0
9
0
% F
% Gly:
9
0
17
9
0
0
9
0
0
9
34
42
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
9
9
0
0
9
0
0
9
9
0
9
0
9
% I
% Lys:
0
0
0
9
9
0
0
0
9
0
0
0
9
0
17
% K
% Leu:
9
0
50
25
0
0
9
9
9
0
0
9
0
0
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
0
0
17
0
9
0
% N
% Pro:
0
0
9
17
9
17
9
0
0
17
0
0
9
17
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
17
0
0
0
42
9
0
0
9
9
0
0
34
9
9
% R
% Ser:
25
9
0
9
0
9
0
25
9
0
0
0
0
0
9
% S
% Thr:
0
0
0
0
9
25
0
17
17
0
0
0
17
9
0
% T
% Val:
0
9
9
17
9
0
0
0
9
34
17
0
0
0
17
% V
% Trp:
0
17
0
0
0
9
0
9
0
0
0
0
0
42
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
17
17
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _