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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH5A1
All Species:
22.73
Human Site:
T405
Identified Species:
45.45
UniProt:
P51649
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51649
NP_001071.1
535
57215
T405
D
A
V
S
K
G
A
T
V
V
T
G
G
K
R
Chimpanzee
Pan troglodytes
Q6A2H0
535
57110
T405
D
A
V
S
K
G
A
T
V
V
T
G
G
K
R
Rhesus Macaque
Macaca mulatta
XP_001101142
535
56988
T405
D
A
V
S
K
G
A
T
I
V
T
G
G
K
R
Dog
Lupus familis
XP_545368
482
51416
L362
T
G
G
K
R
H
Q
L
G
K
N
F
F
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWF0
523
55950
T393
D
A
V
A
K
G
A
T
V
V
T
G
G
K
R
Rat
Rattus norvegicus
P51650
523
56113
T393
D
A
V
A
K
G
A
T
V
V
T
G
G
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418909
548
57904
S418
D
A
V
S
Q
G
A
S
V
V
T
G
G
K
R
Frog
Xenopus laevis
Q6GNL7
902
99964
K771
T
G
V
K
E
G
G
K
L
V
Y
G
G
K
Q
Zebra Danio
Brachydanio rerio
XP_002664997
514
55133
G383
V
A
D
A
V
D
H
G
A
V
V
V
R
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789239
489
52301
L369
V
G
G
K
R
H
A
L
G
G
S
F
F
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SAK4
528
56541
K395
D
A
V
S
K
G
A
K
I
I
I
G
G
K
R
Baker's Yeast
Sacchar. cerevisiae
P38067
497
54171
V363
A
I
D
K
G
A
K
V
V
L
E
G
G
R
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.4
76.4
N.A.
83.9
84.6
N.A.
N.A.
72.6
24.1
68.2
N.A.
N.A.
N.A.
N.A.
55.1
Protein Similarity:
100
99.6
97.5
81.8
N.A.
88.4
89.3
N.A.
N.A.
81.9
36.8
80.7
N.A.
N.A.
N.A.
N.A.
70.4
P-Site Identity:
100
100
93.3
0
N.A.
93.3
93.3
N.A.
N.A.
86.6
40
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
100
60
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.1
44.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
71.2
60.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
73.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
67
0
25
0
9
67
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
59
0
17
0
0
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
0
0
9
0
0
17
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
17
17
0
0
% F
% Gly:
0
25
17
0
9
67
9
9
17
9
0
75
75
9
9
% G
% His:
0
0
0
0
0
17
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
17
9
9
0
0
0
0
% I
% Lys:
0
0
0
34
50
0
9
17
0
9
0
0
0
67
0
% K
% Leu:
0
0
0
0
0
0
0
17
9
9
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% P
% Gln:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
17
0
0
0
0
0
0
0
9
9
59
% R
% Ser:
0
0
0
42
0
0
0
9
0
0
9
0
0
0
0
% S
% Thr:
17
0
0
0
0
0
0
42
0
0
50
0
0
0
0
% T
% Val:
17
0
67
0
9
0
0
9
50
67
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _