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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH5A1
All Species:
30.91
Human Site:
Y469
Identified Species:
61.82
UniProt:
P51649
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51649
NP_001071.1
535
57215
Y469
A
D
V
G
L
A
G
Y
F
Y
S
Q
D
P
A
Chimpanzee
Pan troglodytes
Q6A2H0
535
57110
Y469
A
D
V
G
L
A
G
Y
F
Y
S
Q
D
P
A
Rhesus Macaque
Macaca mulatta
XP_001101142
535
56988
Y469
T
D
V
G
L
A
G
Y
F
Y
S
Q
D
P
A
Dog
Lupus familis
XP_545368
482
51416
I425
Y
S
Q
D
P
A
Q
I
W
R
V
A
E
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWF0
523
55950
Y457
A
E
V
G
L
A
G
Y
F
Y
S
Q
D
P
A
Rat
Rattus norvegicus
P51650
523
56113
Y457
A
D
V
G
L
A
G
Y
F
Y
S
Q
D
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418909
548
57904
Y482
A
D
V
G
L
A
G
Y
F
Y
S
Q
D
P
A
Frog
Xenopus laevis
Q6GNL7
902
99964
G837
S
E
F
G
L
A
S
G
V
F
T
K
D
I
N
Zebra Danio
Brachydanio rerio
XP_002664997
514
55133
Y447
S
P
V
G
L
A
G
Y
F
Y
S
R
D
M
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789239
489
52301
I432
Y
S
N
N
I
G
Q
I
W
R
V
A
E
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SAK4
528
56541
Y459
T
I
A
G
L
A
A
Y
I
F
T
N
S
V
Q
Baker's Yeast
Sacchar. cerevisiae
P38067
497
54171
Y427
T
E
F
G
L
A
A
Y
V
F
S
K
N
V
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.4
76.4
N.A.
83.9
84.6
N.A.
N.A.
72.6
24.1
68.2
N.A.
N.A.
N.A.
N.A.
55.1
Protein Similarity:
100
99.6
97.5
81.8
N.A.
88.4
89.3
N.A.
N.A.
81.9
36.8
80.7
N.A.
N.A.
N.A.
N.A.
70.4
P-Site Identity:
100
100
93.3
6.6
N.A.
93.3
100
N.A.
N.A.
100
26.6
73.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
20
N.A.
100
100
N.A.
N.A.
100
60
86.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.1
44.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
71.2
60.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
0
9
0
0
92
17
0
0
0
0
17
0
0
59
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
42
0
9
0
0
0
0
0
0
0
0
67
0
0
% D
% Glu:
0
25
0
0
0
0
0
0
0
0
0
0
17
0
0
% E
% Phe:
0
0
17
0
0
0
0
0
59
25
0
0
0
0
0
% F
% Gly:
0
0
0
84
0
9
59
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
9
0
0
17
9
0
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
17
0
9
0
% K
% Leu:
0
0
0
0
84
0
0
0
0
0
0
0
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
9
9
0
0
0
0
0
0
0
9
9
0
17
% N
% Pro:
0
9
0
0
9
0
0
0
0
0
0
0
0
50
0
% P
% Gln:
0
0
9
0
0
0
17
0
0
0
0
50
0
9
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
17
0
9
0
0
0
% R
% Ser:
17
17
0
0
0
0
9
0
0
0
67
0
9
0
0
% S
% Thr:
25
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% T
% Val:
0
0
59
0
0
0
0
0
17
0
17
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% W
% Tyr:
17
0
0
0
0
0
0
75
0
59
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _