KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH5A1
All Species:
41.49
Human Site:
Y529
Identified Species:
82.99
UniProt:
P51649
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51649
NP_001071.1
535
57215
Y529
D
E
Y
L
E
L
K
Y
V
C
Y
G
G
L
_
Chimpanzee
Pan troglodytes
Q6A2H0
535
57110
Y529
D
E
Y
L
E
L
K
Y
V
C
Y
G
G
L
_
Rhesus Macaque
Macaca mulatta
XP_001101142
535
56988
Y529
D
E
Y
L
E
L
K
Y
V
C
Y
G
G
L
_
Dog
Lupus familis
XP_545368
482
51416
Y476
D
E
Y
L
E
L
K
Y
V
C
F
G
G
L
_
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWF0
523
55950
Y517
D
E
Y
L
E
V
K
Y
V
C
Y
G
G
L
_
Rat
Rattus norvegicus
P51650
523
56113
Y517
D
E
Y
L
E
V
K
Y
V
C
Y
G
G
L
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418909
548
57904
Y542
D
E
Y
L
E
I
K
Y
V
C
F
G
G
L
_
Frog
Xenopus laevis
Q6GNL7
902
99964
Zebra Danio
Brachydanio rerio
XP_002664997
514
55133
Y507
D
E
Y
L
E
I
K
Y
M
C
L
G
G
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789239
489
52301
Y483
D
E
Y
Q
E
I
K
Y
V
C
F
G
G
I
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SAK4
528
56541
Y519
D
E
Y
L
E
I
K
Y
V
C
L
G
D
M
N
Baker's Yeast
Sacchar. cerevisiae
P38067
497
54171
T487
E
D
Y
T
V
L
K
T
I
T
I
G
N
L
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.4
76.4
N.A.
83.9
84.6
N.A.
N.A.
72.6
24.1
68.2
N.A.
N.A.
N.A.
N.A.
55.1
Protein Similarity:
100
99.6
97.5
81.8
N.A.
88.4
89.3
N.A.
N.A.
81.9
36.8
80.7
N.A.
N.A.
N.A.
N.A.
70.4
P-Site Identity:
100
100
100
92.8
N.A.
92.8
92.8
N.A.
N.A.
85.7
0
73.3
N.A.
N.A.
N.A.
N.A.
71.4
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
0
86.6
N.A.
N.A.
N.A.
N.A.
92.8
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.1
44.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
71.2
60.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
84
0
0
0
0
0
% C
% Asp:
84
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
9
84
0
0
84
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
92
75
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
34
0
0
9
0
9
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
92
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
75
0
42
0
0
0
0
17
0
0
75
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% S
% Thr:
0
0
0
9
0
0
0
9
0
9
0
0
0
0
0
% T
% Val:
0
0
0
0
9
17
0
0
75
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
92
0
0
0
0
84
0
0
42
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
67
% _