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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPC3
All Species:
22.12
Human Site:
S190
Identified Species:
54.07
UniProt:
P51654
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51654
NP_004475.1
580
65563
S190
M
N
P
G
L
P
D
S
A
L
D
I
N
E
C
Chimpanzee
Pan troglodytes
A5A6P7
580
65546
S190
M
N
P
G
L
P
D
S
A
L
D
I
N
E
C
Rhesus Macaque
Macaca mulatta
XP_001097558
580
65585
S190
M
N
P
G
L
P
D
S
A
L
D
I
N
E
C
Dog
Lupus familis
XP_538178
580
65208
S190
M
N
P
G
L
P
E
S
A
L
D
I
N
E
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFZ4
579
65313
S189
M
N
P
G
L
P
E
S
V
L
D
I
N
E
C
Rat
Rattus norvegicus
P13265
597
67030
S189
M
N
P
G
L
P
E
S
V
L
D
I
N
E
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514628
576
65236
I187
I
N
P
G
F
P
E
I
S
L
E
M
T
E
C
Chicken
Gallus gallus
P50593
550
61065
D183
N
A
Q
Y
H
I
T
D
E
Y
L
D
C
M
V
Frog
Xenopus laevis
NP_001084188
556
63021
D184
N
P
Q
Y
Q
F
T
D
E
Y
L
E
C
V
S
Zebra Danio
Brachydanio rerio
XP_688014
590
64494
G185
L
G
N
G
A
V
A
G
I
S
E
E
C
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
99.3
95.5
N.A.
93.9
90.7
N.A.
72.2
22
24.8
42.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
99.8
97.4
N.A.
96.7
93.3
N.A.
82.5
43.6
44.6
58.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
46.6
0
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
80
0
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
0
10
0
40
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
30
0
70
% C
% Asp:
0
0
0
0
0
0
30
20
0
0
60
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
40
0
20
0
20
20
0
70
0
% E
% Phe:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
80
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
10
0
10
10
0
0
60
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
60
0
0
0
0
70
20
0
0
10
0
% L
% Met:
60
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% M
% Asn:
20
70
10
0
0
0
0
0
0
0
0
0
60
0
0
% N
% Pro:
0
10
70
0
0
70
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
20
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
60
10
10
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
20
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
10
0
0
20
0
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
20
0
0
0
0
0
20
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _