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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPC3 All Species: 24.24
Human Site: S95 Identified Species: 59.26
UniProt: P51654 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51654 NP_004475.1 580 65563 S95 N M E Q L L Q S A S M E L K F
Chimpanzee Pan troglodytes A5A6P7 580 65546 S95 N M E Q L L Q S A S K E L K F
Rhesus Macaque Macaca mulatta XP_001097558 580 65585 S95 N M E Q L L Q S A S M E L K F
Dog Lupus familis XP_538178 580 65208 S95 N I E Q L L Q S A S M E L K F
Cat Felis silvestris
Mouse Mus musculus Q8CFZ4 579 65313 S94 N M E Q L L Q S A S M E L K F
Rat Rattus norvegicus P13265 597 67030 S94 N M E Q L L Q S A S M E L K F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514628 576 65236 Q103 E L K F L I I Q N A A V F Q E
Chicken Gallus gallus P50593 550 61065 A99 S V Q T I L T A Q Y K S F D N
Frog Xenopus laevis NP_001084188 556 63021 S100 N M Q H I F A S R F N K F D E
Zebra Danio Brachydanio rerio XP_688014 590 64494 N102 L K G L I I Q N A A L F Q E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 99.3 95.5 N.A. 93.9 90.7 N.A. 72.2 22 24.8 42.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 99.8 97.4 N.A. 96.7 93.3 N.A. 82.5 43.6 44.6 58.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 100 93.3 N.A. 100 100 N.A. 6.6 6.6 20 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 100 100 N.A. 100 100 N.A. 40 40 40 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 10 70 20 10 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % D
% Glu: 10 0 60 0 0 0 0 0 0 0 0 60 0 10 20 % E
% Phe: 0 0 0 10 0 10 0 0 0 10 0 10 30 0 60 % F
% Gly: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 30 20 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 10 0 0 0 0 0 0 0 20 10 0 60 0 % K
% Leu: 10 10 0 10 70 70 0 0 0 0 10 0 60 0 0 % L
% Met: 0 60 0 0 0 0 0 0 0 0 50 0 0 0 0 % M
% Asn: 70 0 0 0 0 0 0 10 10 0 10 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 20 60 0 0 70 10 10 0 0 0 10 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 10 0 0 0 0 0 0 70 0 60 0 10 0 0 0 % S
% Thr: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _