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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPC3 All Species: 27.88
Human Site: Y361 Identified Species: 68.15
UniProt: P51654 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51654 NP_004475.1 580 65563 Y361 Q R Q Y R S A Y Y P E D L F I
Chimpanzee Pan troglodytes A5A6P7 580 65546 Y361 Q R Q Y R S A Y Y P E D L F I
Rhesus Macaque Macaca mulatta XP_001097558 580 65585 Y361 Q R Q Y R S A Y Y P E D L F I
Dog Lupus familis XP_538178 580 65208 Y361 Q R Q Y R S A Y Y P E D L F I
Cat Felis silvestris
Mouse Mus musculus Q8CFZ4 579 65313 Y360 Q R Q Y R S A Y Y P E D L F I
Rat Rattus norvegicus P13265 597 67030 Y360 Q R Q Y R S A Y Y P E D L F I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514628 576 65236 Y358 P R Q Y R S A Y Y P E D L F I
Chicken Gallus gallus P50593 550 61065 S352 V S M K G S S S E D K K R R G
Frog Xenopus laevis NP_001084188 556 63021 R353 L S Q G R Q A R S V S D T N F
Zebra Danio Brachydanio rerio XP_688014 590 64494 P354 P R V S R A V P V S A E H T S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 99.3 95.5 N.A. 93.9 90.7 N.A. 72.2 22 24.8 42.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 99.8 97.4 N.A. 96.7 93.3 N.A. 82.5 43.6 44.6 58.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 6.6 26.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 20 26.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 80 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 80 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 70 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 70 10 % F
% Gly: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 10 10 0 0 0 % K
% Leu: 10 0 0 0 0 0 0 0 0 0 0 0 70 0 0 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 20 0 0 0 0 0 0 10 0 70 0 0 0 0 0 % P
% Gln: 60 0 80 0 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 80 0 0 90 0 0 10 0 0 0 0 10 10 0 % R
% Ser: 0 20 0 10 0 80 10 10 10 10 10 0 0 0 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % T
% Val: 10 0 10 0 0 0 10 0 10 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 70 0 0 0 70 70 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _