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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSD17B4
All Species:
49.7
Human Site:
S107
Identified Species:
84.1
UniProt:
P51659
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51659
NP_000405.1
736
79686
S107
A
G
I
L
R
D
R
S
F
A
R
I
S
D
E
Chimpanzee
Pan troglodytes
XP_517892
712
77651
S83
A
G
I
L
R
D
R
S
F
A
R
I
S
D
E
Rhesus Macaque
Macaca mulatta
XP_001087837
734
79298
S107
A
G
I
L
R
D
R
S
F
A
R
I
S
D
E
Dog
Lupus familis
XP_531860
737
79671
S108
A
G
I
L
R
D
S
S
F
G
R
I
S
D
E
Cat
Felis silvestris
Mouse
Mus musculus
P51660
735
79463
S107
A
G
I
L
R
D
R
S
F
S
R
I
S
D
E
Rat
Rattus norvegicus
P97852
735
79409
S107
A
G
I
L
R
D
R
S
F
S
R
I
S
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512505
752
82654
S111
A
G
I
L
R
D
R
S
F
V
R
I
S
D
H
Chicken
Gallus gallus
NP_990274
735
80130
S107
A
G
I
L
R
D
R
S
F
V
R
I
S
D
E
Frog
Xenopus laevis
NP_001086063
741
80382
S108
A
G
I
L
R
D
R
S
F
A
R
I
S
D
A
Zebra Danio
Brachydanio rerio
NP_956430
725
78606
S107
A
G
I
L
R
D
R
S
F
A
R
T
S
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573109
598
64055
R13
G
K
L
R
Y
D
G
R
V
A
V
V
T
G
A
Honey Bee
Apis mellifera
XP_393475
704
78091
S108
A
G
I
L
R
D
K
S
F
A
K
M
L
E
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q02207
900
98685
S108
A
G
I
L
R
D
V
S
F
A
K
M
T
E
R
Red Bread Mold
Neurospora crassa
Q01373
894
96308
S107
A
G
I
L
R
D
I
S
F
K
N
M
K
D
E
Conservation
Percent
Protein Identity:
100
94.8
97.2
87.2
N.A.
86.2
87.3
N.A.
68
71.3
70.7
68
N.A.
45.3
50
N.A.
N.A.
Protein Similarity:
100
95.7
98.5
92.6
N.A.
93.3
93.7
N.A.
81.3
83.8
83.8
81.5
N.A.
59
67.1
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
86.6
93.3
93.3
86.6
N.A.
13.3
60
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
86.6
93.3
93.3
86.6
N.A.
33.3
86.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.4
29.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46
45.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
86.6
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
93
0
0
0
0
0
0
0
0
58
0
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
100
0
0
0
0
0
0
0
79
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
58
% E
% Phe:
0
0
0
0
0
0
0
0
93
0
0
0
0
0
0
% F
% Gly:
8
93
0
0
0
0
8
0
0
8
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
93
0
0
0
8
0
0
0
0
65
0
0
0
% I
% Lys:
0
8
0
0
0
0
8
0
0
8
15
0
8
0
0
% K
% Leu:
0
0
8
93
0
0
0
0
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
22
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
93
0
65
8
0
0
72
0
0
0
8
% R
% Ser:
0
0
0
0
0
0
8
93
0
15
0
0
72
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
8
15
0
0
% T
% Val:
0
0
0
0
0
0
8
0
8
15
8
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _