KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSD17B4
All Species:
44.85
Human Site:
S508
Identified Species:
75.9
UniProt:
P51659
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51659
NP_000405.1
736
79686
S508
Q
A
A
L
Y
R
L
S
G
D
W
N
P
L
H
Chimpanzee
Pan troglodytes
XP_517892
712
77651
S484
Q
A
A
L
Y
R
L
S
G
D
W
N
P
L
H
Rhesus Macaque
Macaca mulatta
XP_001087837
734
79298
S506
Q
A
A
L
Y
R
L
S
G
D
W
N
P
L
H
Dog
Lupus familis
XP_531860
737
79671
S509
Q
A
A
L
Y
R
L
S
G
D
W
N
P
L
H
Cat
Felis silvestris
Mouse
Mus musculus
P51660
735
79463
S507
Q
A
A
L
Y
R
L
S
G
D
W
N
P
L
H
Rat
Rattus norvegicus
P97852
735
79409
S507
Q
A
A
L
Y
R
L
S
G
D
S
N
P
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512505
752
82654
S512
Q
A
A
L
Y
R
L
S
G
D
W
N
P
L
H
Chicken
Gallus gallus
NP_990274
735
80130
S508
Q
A
A
L
Y
R
L
S
G
D
W
N
P
L
H
Frog
Xenopus laevis
NP_001086063
741
80382
S511
Q
A
A
L
Y
R
L
S
G
D
W
N
P
L
H
Zebra Danio
Brachydanio rerio
NP_956430
725
78606
S501
Q
A
A
L
Y
R
L
S
G
D
W
N
P
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573109
598
64055
G391
D
F
S
N
I
L
H
G
E
Q
Y
L
E
I
V
Honey Bee
Apis mellifera
XP_393475
704
78091
S497
Q
A
A
L
Y
R
L
S
G
D
Q
N
P
L
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q02207
900
98685
L638
C
I
L
Y
N
L
G
L
G
C
T
S
K
E
L
Red Bread Mold
Neurospora crassa
Q01373
894
96308
A593
D
S
I
E
K
I
M
A
N
M
E
N
R
V
G
Conservation
Percent
Protein Identity:
100
94.8
97.2
87.2
N.A.
86.2
87.3
N.A.
68
71.3
70.7
68
N.A.
45.3
50
N.A.
N.A.
Protein Similarity:
100
95.7
98.5
92.6
N.A.
93.3
93.7
N.A.
81.3
83.8
83.8
81.5
N.A.
59
67.1
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
100
100
100
100
N.A.
0
93.3
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
100
100
100
100
N.A.
20
93.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.4
29.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46
45.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
79
79
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
15
0
0
0
0
0
0
0
0
79
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
8
0
8
0
8
8
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
8
86
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
79
% H
% Ile:
0
8
8
0
8
8
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
0
8
79
0
15
79
8
0
0
0
8
0
79
8
% L
% Met:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
0
0
0
8
0
0
86
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
79
0
0
% P
% Gln:
79
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
79
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
8
8
0
0
0
0
79
0
0
8
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
65
0
0
0
0
% W
% Tyr:
0
0
0
8
79
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _