KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSD17B4
All Species:
52.42
Human Site:
T149
Identified Species:
88.72
UniProt:
P51659
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51659
NP_000405.1
736
79686
T149
K
Y
G
R
I
I
M
T
S
S
A
S
G
I
Y
Chimpanzee
Pan troglodytes
XP_517892
712
77651
T125
K
Y
G
R
I
I
M
T
S
S
A
S
G
I
Y
Rhesus Macaque
Macaca mulatta
XP_001087837
734
79298
T149
K
Y
G
R
I
I
M
T
S
S
A
S
G
I
Y
Dog
Lupus familis
XP_531860
737
79671
T150
K
F
G
R
I
V
M
T
S
S
A
S
G
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
P51660
735
79463
T149
N
Y
G
R
I
L
M
T
S
S
A
S
G
I
Y
Rat
Rattus norvegicus
P97852
735
79409
T149
N
Y
G
R
I
I
M
T
A
S
A
S
G
I
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512505
752
82654
T153
N
F
G
R
I
I
M
T
S
S
A
A
G
I
Y
Chicken
Gallus gallus
NP_990274
735
80130
T149
K
F
G
R
I
I
M
T
S
S
A
A
G
I
Y
Frog
Xenopus laevis
NP_001086063
741
80382
T150
K
F
G
R
I
I
M
T
S
S
A
A
G
I
Y
Zebra Danio
Brachydanio rerio
NP_956430
725
78606
T149
K
F
G
R
I
I
M
T
S
S
A
A
G
I
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573109
598
64055
Q55
H
S
G
D
G
A
S
Q
R
A
A
D
I
V
V
Honey Bee
Apis mellifera
XP_393475
704
78091
T150
K
Y
G
R
I
I
M
T
A
S
N
S
G
L
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q02207
900
98685
T150
K
F
G
R
I
I
N
T
A
S
P
A
G
L
F
Red Bread Mold
Neurospora crassa
Q01373
894
96308
T149
K
F
G
R
V
I
N
T
A
S
A
A
G
L
F
Conservation
Percent
Protein Identity:
100
94.8
97.2
87.2
N.A.
86.2
87.3
N.A.
68
71.3
70.7
68
N.A.
45.3
50
N.A.
N.A.
Protein Similarity:
100
95.7
98.5
92.6
N.A.
93.3
93.7
N.A.
81.3
83.8
83.8
81.5
N.A.
59
67.1
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
80
86.6
86.6
86.6
N.A.
13.3
80
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
100
100
100
N.A.
26.6
93.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.4
29.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46
45.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
86.6
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
29
8
86
43
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
15
% F
% Gly:
0
0
100
0
8
0
0
0
0
0
0
0
93
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
86
79
0
0
0
0
0
0
8
72
0
% I
% Lys:
72
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
8
0
0
0
0
0
0
0
22
0
% L
% Met:
0
0
0
0
0
0
79
0
0
0
0
0
0
0
0
% M
% Asn:
22
0
0
0
0
0
15
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
93
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
8
0
65
93
0
50
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
93
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
8
0
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
43
0
0
0
0
0
0
0
0
0
0
0
0
79
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _