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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE2D1 All Species: 50.61
Human Site: S22 Identified Species: 92.78
UniProt: P51668 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51668 NP_003329.1 147 16602 S22 R D P P A H C S A G P V G D D
Chimpanzee Pan troglodytes XP_517826 147 16727 S22 R D P P A Q C S A G P V G D D
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P61079 147 16669 S22 R D P P A Q C S A G P V G D D
Rat Rattus norvegicus P62839 147 16717 S22 R D P P A Q C S A G P V G D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518541 589 64085 S288 R D P P A Q C S A G P V G D D
Chicken Gallus gallus XP_414470 265 28856 S140 R D P P A Q C S A P P V G D D
Frog Xenopus laevis NP_001093355 147 16659 S22 R D P P A Q C S A G P V G E D
Zebra Danio Brachydanio rerio NP_955958 147 16617 S22 R D P P A Q C S A G P V G D D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25867 147 16660 S22 R D P P A Q C S A G P V G D D
Honey Bee Apis mellifera XP_001120139 147 16660 S22 R D P P A Q C S A G P V G D D
Nematode Worm Caenorhab. elegans P35129 147 16687 S22 R D P P A Q C S A G P V G D D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P35134 148 16533 S22 K D P P S N C S A G P V A E D
Baker's Yeast Sacchar. cerevisiae P15732 148 16262 S23 R D P P A S C S A G P V G D D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87 N.A. N.A. N.A. 88.4 89.1 N.A. 21.5 48.6 90.4 94.5 N.A. 89.1 88.4 89.1 N.A.
Protein Similarity: 100 94.5 N.A. N.A. N.A. 95.9 95.9 N.A. 24.2 52.8 95.2 95.9 N.A. 95.2 95.2 96.5 N.A.
P-Site Identity: 100 93.3 N.A. N.A. N.A. 93.3 93.3 N.A. 93.3 86.6 86.6 93.3 N.A. 93.3 93.3 93.3 N.A.
P-Site Similarity: 100 93.3 N.A. N.A. N.A. 93.3 93.3 N.A. 93.3 86.6 93.3 93.3 N.A. 93.3 93.3 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 75.6 79 N.A.
Protein Similarity: N.A. N.A. N.A. 87.8 89.1 N.A.
P-Site Identity: N.A. N.A. N.A. 66.6 93.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 93.3 93.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 93 0 0 0 100 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % C
% Asp: 0 100 0 0 0 0 0 0 0 0 0 0 0 85 100 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 93 0 0 93 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 100 100 0 0 0 0 0 8 100 0 0 0 0 % P
% Gln: 0 0 0 0 0 77 0 0 0 0 0 0 0 0 0 % Q
% Arg: 93 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 8 8 0 100 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _