KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCR4
All Species:
24.24
Human Site:
T74
Identified Species:
76.19
UniProt:
P51679
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51679
NP_005499.1
360
41403
T74
Y
K
R
L
R
S
M
T
D
V
Y
L
L
N
L
Chimpanzee
Pan troglodytes
P56440
352
40521
S75
Y
L
L
N
L
A
I
S
D
L
F
F
L
L
T
Rhesus Macaque
Macaca mulatta
O18793
360
41121
T77
C
K
K
L
K
S
L
T
D
I
Y
L
L
N
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P51680
360
41444
T74
Y
K
R
L
K
S
M
T
D
V
Y
L
L
N
L
Rat
Rattus norvegicus
O55193
373
42745
T90
C
K
K
L
K
S
M
T
D
I
Y
L
F
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514912
361
41083
T75
Y
K
R
L
R
S
M
T
D
V
Y
L
L
N
L
Chicken
Gallus gallus
XP_426017
358
41564
T75
Y
K
R
L
K
S
M
T
D
V
Y
L
L
N
L
Frog
Xenopus laevis
NP_001088014
352
40801
I77
I
Y
L
L
N
L
A
I
S
D
L
L
F
V
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.6
47.2
N.A.
N.A.
85.8
46.6
N.A.
73.1
57.2
45.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
68
67.2
N.A.
N.A.
93.6
67.2
N.A.
85.8
73.6
65.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
66.6
N.A.
N.A.
93.3
66.6
N.A.
100
93.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
53.3
93.3
N.A.
N.A.
100
86.6
N.A.
100
100
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
13
13
0
0
0
0
0
0
0
0
% A
% Cys:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
88
13
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
13
13
25
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
0
0
0
0
13
13
0
25
0
0
0
0
13
% I
% Lys:
0
75
25
0
50
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
13
25
88
13
13
13
0
0
13
13
88
75
13
75
% L
% Met:
0
0
0
0
0
0
63
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
13
13
0
0
0
0
0
0
0
0
75
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
50
0
25
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
75
0
13
13
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
75
0
0
0
0
0
0
13
% T
% Val:
0
0
0
0
0
0
0
0
0
50
0
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
63
13
0
0
0
0
0
0
0
0
75
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _