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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGSH All Species: 7.88
Human Site: S364 Identified Species: 19.26
UniProt: P51688 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51688 NP_000190.1 502 56695 S364 L W A T V F G S Q S H H E V T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001110101 502 56546 S364 L W A T V F G S Q S H H E V T
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P50428 506 53758 S371 T G K S P R K S V F F Y P P Y
Rat Rattus norvegicus Q32KJ6 524 58284 D381 M L Q G H I I D R P I F Y Y R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510198 185 21881 L69 V L H R Q L R L V H N L N F K
Chicken Gallus gallus Q5ZK90 535 61383 E388 S L L P L L L E K A E D E V P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q08CJ7 523 59480 G401 W A F S E Y H G C N A N T S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650760 524 59888 H367 V F G S H S Y H E V T M A Y P
Honey Bee Apis mellifera XP_623278 490 56473 T345 Q E P I E N N T A I F A S Q T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796819 504 57529 S362 G W N V S L S S H D L H E I T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96 N.A. N.A. 24.7 22.8 N.A. 29.4 21.8 N.A. 21 N.A. 52 59.5 N.A. 60.3
Protein Similarity: 100 N.A. 97.4 N.A. N.A. 40.1 37 N.A. 32 38.6 N.A. 38.2 N.A. 64.8 73.9 N.A. 74.8
P-Site Identity: 100 N.A. 100 N.A. N.A. 6.6 0 N.A. 0 13.3 N.A. 6.6 N.A. 0 6.6 N.A. 33.3
P-Site Similarity: 100 N.A. 100 N.A. N.A. 20 13.3 N.A. 13.3 33.3 N.A. 33.3 N.A. 26.6 13.3 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 20 0 0 0 0 0 10 10 10 10 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 0 10 0 10 0 0 0 % D
% Glu: 0 10 0 0 20 0 0 10 10 0 10 0 40 0 0 % E
% Phe: 0 10 10 0 0 20 0 0 0 10 20 10 0 10 0 % F
% Gly: 10 10 10 10 0 0 20 10 0 0 0 0 0 0 0 % G
% His: 0 0 10 0 20 0 10 10 10 10 20 30 0 0 0 % H
% Ile: 0 0 0 10 0 10 10 0 0 10 10 0 0 10 0 % I
% Lys: 0 0 10 0 0 0 10 0 10 0 0 0 0 0 10 % K
% Leu: 20 30 10 0 10 30 10 10 0 0 10 10 0 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 10 0 0 10 10 0 0 10 10 10 10 0 0 % N
% Pro: 0 0 10 10 10 0 0 0 0 10 0 0 10 10 20 % P
% Gln: 10 0 10 0 10 0 0 0 20 0 0 0 0 10 0 % Q
% Arg: 0 0 0 10 0 10 10 0 10 0 0 0 0 0 10 % R
% Ser: 10 0 0 30 10 10 10 40 0 20 0 0 10 10 0 % S
% Thr: 10 0 0 20 0 0 0 10 0 0 10 0 10 0 50 % T
% Val: 20 0 0 10 20 0 0 0 20 10 0 0 0 30 0 % V
% Trp: 10 30 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 10 0 0 0 0 10 10 20 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _