KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGSH
All Species:
4.55
Human Site:
S373
Identified Species:
11.11
UniProt:
P51688
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51688
NP_000190.1
502
56695
S373
S
H
H
E
V
T
M
S
Y
P
M
R
S
V
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110101
502
56546
S373
S
H
H
E
V
T
M
S
Y
P
M
R
S
V
Q
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P50428
506
53758
D380
F
F
Y
P
P
Y
P
D
E
I
H
G
V
F
A
Rat
Rattus norvegicus
Q32KJ6
524
58284
N390
P
I
F
Y
Y
R
G
N
T
L
M
A
V
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510198
185
21881
P78
H
N
L
N
F
K
M
P
F
P
I
D
Q
D
F
Chicken
Gallus gallus
Q5ZK90
535
61383
R397
A
E
D
E
V
P
R
R
G
P
R
P
S
W
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q08CJ7
523
59480
M410
N
A
N
T
S
T
Y
M
L
R
I
A
E
W
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650760
524
59888
R376
V
T
M
A
Y
P
M
R
M
V
R
N
R
R
Y
Honey Bee
Apis mellifera
XP_623278
490
56473
H354
I
F
A
S
Q
T
H
H
E
I
T
M
Y
Y
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796819
504
57529
F371
D
L
H
E
I
T
M
F
Y
P
Q
R
V
I
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96
N.A.
N.A.
24.7
22.8
N.A.
29.4
21.8
N.A.
21
N.A.
52
59.5
N.A.
60.3
Protein Similarity:
100
N.A.
97.4
N.A.
N.A.
40.1
37
N.A.
32
38.6
N.A.
38.2
N.A.
64.8
73.9
N.A.
74.8
P-Site Identity:
100
N.A.
100
N.A.
N.A.
0
6.6
N.A.
13.3
26.6
N.A.
6.6
N.A.
6.6
6.6
N.A.
46.6
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
6.6
13.3
N.A.
33.3
33.3
N.A.
33.3
N.A.
6.6
6.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
10
0
0
0
0
0
0
0
20
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
0
0
0
10
0
0
0
10
0
10
0
% D
% Glu:
0
10
0
40
0
0
0
0
20
0
0
0
10
0
0
% E
% Phe:
10
20
10
0
10
0
0
10
10
0
0
0
0
10
10
% F
% Gly:
0
0
0
0
0
0
10
0
10
0
0
10
0
0
0
% G
% His:
10
20
30
0
0
0
10
10
0
0
10
0
0
0
0
% H
% Ile:
10
10
0
0
10
0
0
0
0
20
20
0
0
10
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
10
10
0
0
0
0
0
10
10
0
0
0
0
10
% L
% Met:
0
0
10
0
0
0
50
10
10
0
30
10
0
0
0
% M
% Asn:
10
10
10
10
0
0
0
10
0
0
0
10
0
0
0
% N
% Pro:
10
0
0
10
10
20
10
10
0
50
0
10
0
0
10
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
10
0
10
0
20
% Q
% Arg:
0
0
0
0
0
10
10
20
0
10
20
30
10
10
10
% R
% Ser:
20
0
0
10
10
0
0
20
0
0
0
0
30
0
0
% S
% Thr:
0
10
0
10
0
50
0
0
10
0
10
0
0
10
0
% T
% Val:
10
0
0
0
30
0
0
0
0
10
0
0
30
20
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% W
% Tyr:
0
0
10
10
20
10
10
0
30
0
0
0
10
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _