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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGSH All Species: 14.24
Human Site: S66 Identified Species: 34.81
UniProt: P51688 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51688 NP_000190.1 502 56695 S66 L F R N A F T S V S S C S P S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001110101 502 56546 S66 L F R N A F T S V S S C S P S
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P50428 506 53758 P64 R F T D F Y V P V S L C T P S
Rat Rattus norvegicus Q32KJ6 524 58284 A76 L F P S F Y S A N P L C S P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510198 185 21881
Chicken Gallus gallus Q5ZK90 535 61383 P51 D G R L T F Y P G N Q T V D L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q08CJ7 523 59480 L90 W S G Q F V H L T Q S W N N N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650760 524 59888 S69 F T S V S S C S P S R S Q L L
Honey Bee Apis mellifera XP_623278 490 56473 S47 L F N N A Y S S V S S C S P S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796819 504 57529 S63 V F K H A Y T S V S S C S P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96 N.A. N.A. 24.7 22.8 N.A. 29.4 21.8 N.A. 21 N.A. 52 59.5 N.A. 60.3
Protein Similarity: 100 N.A. 97.4 N.A. N.A. 40.1 37 N.A. 32 38.6 N.A. 38.2 N.A. 64.8 73.9 N.A. 74.8
P-Site Identity: 100 N.A. 100 N.A. N.A. 40 40 N.A. 0 13.3 N.A. 6.6 N.A. 13.3 80 N.A. 73.3
P-Site Similarity: 100 N.A. 100 N.A. N.A. 60 66.6 N.A. 0 20 N.A. 20 N.A. 20 93.3 N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 40 0 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 60 0 0 0 % C
% Asp: 10 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 60 0 0 30 30 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 10 0 0 0 0 0 10 0 0 0 0 0 0 % G
% His: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 40 0 0 10 0 0 0 10 0 0 20 0 0 10 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 30 0 0 0 0 10 10 0 0 10 10 10 % N
% Pro: 0 0 10 0 0 0 0 20 10 10 0 0 0 60 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 10 10 0 10 0 0 % Q
% Arg: 10 0 30 0 0 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 0 10 10 10 10 10 20 50 0 60 50 10 50 0 60 % S
% Thr: 0 10 10 0 10 0 30 0 10 0 0 10 10 0 0 % T
% Val: 10 0 0 10 0 10 10 0 50 0 0 0 10 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 40 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _