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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGSH All Species: 16.67
Human Site: T47 Identified Species: 40.74
UniProt: P51688 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51688 NP_000190.1 502 56695 T47 Y N N S A I A T P H L D A L A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001110101 502 56546 T47 Y N N S A I A T P H L D A L A
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P50428 506 53758 T45 Y G H P S S T T P N L D Q L A
Rat Rattus norvegicus Q32KJ6 524 58284 T57 Y G E P S R E T P N L D R M A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510198 185 21881
Chicken Gallus gallus Q5ZK90 535 61383 R32 R P P R H S S R P N V L L V A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q08CJ7 523 59480 N71 V F L N S Y T N S P I C C P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650760 524 59888 A50 C Q T P N L D A L A K R G L L
Honey Bee Apis mellifera XP_623278 490 56473 T28 Y L N K I C Q T P N L D N L A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796819 504 57529 T44 Y N N T V I K T P H L D A L G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96 N.A. N.A. 24.7 22.8 N.A. 29.4 21.8 N.A. 21 N.A. 52 59.5 N.A. 60.3
Protein Similarity: 100 N.A. 97.4 N.A. N.A. 40.1 37 N.A. 32 38.6 N.A. 38.2 N.A. 64.8 73.9 N.A. 74.8
P-Site Identity: 100 N.A. 100 N.A. N.A. 46.6 40 N.A. 0 13.3 N.A. 0 N.A. 6.6 53.3 N.A. 73.3
P-Site Similarity: 100 N.A. 100 N.A. N.A. 66.6 60 N.A. 0 40 N.A. 26.6 N.A. 13.3 60 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 20 0 20 10 0 10 0 0 30 0 60 % A
% Cys: 10 0 0 0 0 10 0 0 0 0 0 10 10 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 0 60 0 0 0 % D
% Glu: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 20 0 0 0 0 0 0 0 0 0 0 10 0 10 % G
% His: 0 0 10 0 10 0 0 0 0 30 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 30 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 10 0 0 0 10 0 0 0 0 % K
% Leu: 0 10 10 0 0 10 0 0 10 0 60 10 10 60 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 30 40 10 10 0 0 10 0 40 0 0 10 0 0 % N
% Pro: 0 10 10 30 0 0 0 0 70 10 0 0 0 10 0 % P
% Gln: 0 10 0 0 0 0 10 0 0 0 0 0 10 0 0 % Q
% Arg: 10 0 0 10 0 10 0 10 0 0 0 10 10 0 0 % R
% Ser: 0 0 0 20 30 20 10 0 10 0 0 0 0 0 10 % S
% Thr: 0 0 10 10 0 0 20 60 0 0 0 0 0 0 0 % T
% Val: 10 0 0 0 10 0 0 0 0 0 10 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 60 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _