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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGSH All Species: 12.42
Human Site: Y132 Identified Species: 30.37
UniProt: P51688 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51688 NP_000190.1 502 56695 Y132 H V G P E T V Y P F D F A Y T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001110101 502 56546 Y132 H V G P E A V Y P F D F A Y T
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P50428 506 53758 E130 W H L G V G P E G A F L P P H
Rat Rattus norvegicus Q32KJ6 524 58284 W142 T N K I V G K W H L G H R P Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510198 185 21881
Chicken Gallus gallus Q5ZK90 535 61383 M117 Y V T W M D L M Q K H G Y Y T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q08CJ7 523 59480 T156 R Q E G R P V T D L V G D A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650760 524 59888 F135 G A A N N F R F D F E Q T E E
Honey Bee Apis mellifera XP_623278 490 56473 Y113 H I G P S N V Y P F D F S Q T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796819 504 57529 Y129 H V G P E A V Y P F D Y S K T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96 N.A. N.A. 24.7 22.8 N.A. 29.4 21.8 N.A. 21 N.A. 52 59.5 N.A. 60.3
Protein Similarity: 100 N.A. 97.4 N.A. N.A. 40.1 37 N.A. 32 38.6 N.A. 38.2 N.A. 64.8 73.9 N.A. 74.8
P-Site Identity: 100 N.A. 93.3 N.A. N.A. 0 0 N.A. 0 20 N.A. 6.6 N.A. 6.6 66.6 N.A. 73.3
P-Site Similarity: 100 N.A. 93.3 N.A. N.A. 0 6.6 N.A. 0 33.3 N.A. 13.3 N.A. 20 80 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 0 20 0 0 0 10 0 0 20 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 20 0 40 0 10 0 0 % D
% Glu: 0 0 10 0 30 0 0 10 0 0 10 0 0 10 10 % E
% Phe: 0 0 0 0 0 10 0 10 0 50 10 30 0 0 0 % F
% Gly: 10 0 40 20 0 20 0 0 10 0 10 20 0 0 0 % G
% His: 40 10 0 0 0 0 0 0 10 0 10 10 0 0 10 % H
% Ile: 0 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 10 0 0 10 0 0 0 10 0 % K
% Leu: 0 0 10 0 0 0 10 0 0 20 0 10 0 0 0 % L
% Met: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 10 10 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 40 0 10 10 0 40 0 0 0 10 20 0 % P
% Gln: 0 10 0 0 0 0 0 0 10 0 0 10 0 10 10 % Q
% Arg: 10 0 0 0 10 0 10 0 0 0 0 0 10 0 0 % R
% Ser: 0 0 0 0 10 0 0 0 0 0 0 0 20 0 10 % S
% Thr: 10 0 10 0 0 10 0 10 0 0 0 0 10 0 50 % T
% Val: 0 40 0 0 20 0 50 0 0 0 10 0 0 0 0 % V
% Trp: 10 0 0 10 0 0 0 10 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 40 0 0 0 10 10 30 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _