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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGSH
All Species:
8.18
Human Site:
Y174
Identified Species:
20
UniProt:
P51688
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51688
NP_000190.1
502
56695
Y174
D
D
R
P
F
F
L
Y
V
A
F
H
D
P
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110101
502
56546
Y174
D
D
R
P
F
F
L
Y
V
A
F
H
D
P
H
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P50428
506
53758
D172
I
P
C
K
G
G
C
D
Q
G
L
V
P
I
P
Rat
Rattus norvegicus
Q32KJ6
524
58284
D184
P
N
I
P
V
Y
R
D
W
E
M
V
G
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510198
185
21881
Chicken
Gallus gallus
Q5ZK90
535
61383
R159
F
L
L
R
Q
E
G
R
P
K
V
N
L
T
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q08CJ7
523
59480
G198
Q
P
F
A
L
Y
L
G
L
N
L
P
H
P
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650760
524
59888
M177
E
K
K
P
F
F
L
M
V
G
F
H
D
P
H
Honey Bee
Apis mellifera
XP_623278
490
56473
Y155
K
T
K
P
F
F
L
Y
I
G
F
H
D
P
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796819
504
57529
L171
N
D
T
R
P
F
F
L
Y
I
G
F
H
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96
N.A.
N.A.
24.7
22.8
N.A.
29.4
21.8
N.A.
21
N.A.
52
59.5
N.A.
60.3
Protein Similarity:
100
N.A.
97.4
N.A.
N.A.
40.1
37
N.A.
32
38.6
N.A.
38.2
N.A.
64.8
73.9
N.A.
74.8
P-Site Identity:
100
N.A.
100
N.A.
N.A.
0
6.6
N.A.
0
0
N.A.
13.3
N.A.
66.6
66.6
N.A.
13.3
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
0
20
N.A.
0
6.6
N.A.
33.3
N.A.
80
80
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
20
0
0
0
0
10
% A
% Cys:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
20
30
0
0
0
0
0
20
0
0
0
0
40
10
0
% D
% Glu:
10
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% E
% Phe:
10
0
10
0
40
50
10
0
0
0
40
10
0
0
10
% F
% Gly:
0
0
0
0
10
10
10
10
0
30
10
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
40
20
0
40
% H
% Ile:
10
0
10
0
0
0
0
0
10
10
0
0
0
10
0
% I
% Lys:
10
10
20
10
0
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
0
10
10
0
10
0
50
10
10
0
20
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% M
% Asn:
10
10
0
0
0
0
0
0
0
10
0
10
0
0
0
% N
% Pro:
10
20
0
50
10
0
0
0
10
0
0
10
10
50
10
% P
% Gln:
10
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
20
20
0
0
10
10
0
0
0
0
0
10
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
10
10
0
0
0
0
0
0
0
0
0
0
10
0
% T
% Val:
0
0
0
0
10
0
0
0
30
0
10
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
20
0
30
10
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _