Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARSD All Species: 9.7
Human Site: S284 Identified Species: 23.7
UniProt: P51689 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51689 NP_001660.2 593 64860 S284 L M L K E A V S Y I E R H K H
Chimpanzee Pan troglodytes XP_520911 562 63294 S276 H V H T P L I S K K K F V G H
Rhesus Macaque Macaca mulatta XP_001116129 589 65549 S281 L I L R E V A S F L K R N K H
Dog Lupus familis XP_548838 639 70828 S329 H M L R E A V S Y I E R N K H
Cat Felis silvestris
Mouse Mus musculus P50427 624 66572 L278 R L A D E A A L F L R R N R A
Rat Rattus norvegicus P15589 577 62660 P278 L R R N R D T P F L L F L S F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514413 576 63289 F274 Q R N R K G P F L L F V S L L
Chicken Gallus gallus Q5ZK90 535 61383 G266 S Y T K N C T G E F T K Q E V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q08CJ7 523 59480 V254 P V D Y Y S T V T K N C S G H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P50473 567 62459 D279 T S L F S S D D F S C T S R R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.7 61.3 74.1 N.A. 47.1 48 N.A. 70.3 20.9 N.A. 22.7 N.A. N.A. N.A. N.A. 27.9
Protein Similarity: 100 71.8 71.8 81.2 N.A. 57.3 59.3 N.A. 79.7 36.9 N.A. 38.2 N.A. N.A. N.A. N.A. 42.1
P-Site Identity: 100 13.3 46.6 80 N.A. 20 6.6 N.A. 0 6.6 N.A. 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 33.3 86.6 93.3 N.A. 53.3 20 N.A. 20 20 N.A. 20 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 30 20 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 10 10 0 0 0 % C
% Asp: 0 0 10 10 0 10 10 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 40 0 0 0 10 0 20 0 0 10 0 % E
% Phe: 0 0 0 10 0 0 0 10 40 10 10 20 0 0 10 % F
% Gly: 0 0 0 0 0 10 0 10 0 0 0 0 0 20 0 % G
% His: 20 0 10 0 0 0 0 0 0 0 0 0 10 0 50 % H
% Ile: 0 10 0 0 0 0 10 0 0 20 0 0 0 0 0 % I
% Lys: 0 0 0 20 10 0 0 0 10 20 20 10 0 30 0 % K
% Leu: 30 10 40 0 0 10 0 10 10 40 10 0 10 10 10 % L
% Met: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 10 10 0 0 0 0 0 10 0 30 0 0 % N
% Pro: 10 0 0 0 10 0 10 10 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 10 20 10 30 10 0 0 0 0 0 10 40 0 20 10 % R
% Ser: 10 10 0 0 10 20 0 40 0 10 0 0 30 10 0 % S
% Thr: 10 0 10 10 0 0 30 0 10 0 10 10 0 0 0 % T
% Val: 0 20 0 0 0 10 20 10 0 0 0 10 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 10 10 0 0 0 20 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _