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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARSD All Species: 14.85
Human Site: S533 Identified Species: 36.3
UniProt: P51689 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51689 NP_001660.2 593 64860 S533 A R P L T P D S E P L Y H A V
Chimpanzee Pan troglodytes XP_520911 562 63294 E500 L P L N P D N E P L L D S V I
Rhesus Macaque Macaca mulatta XP_001116129 589 65549 S530 T H V L T P A S E P V F Y Q V
Dog Lupus familis XP_548838 639 70828 S578 A R P L S P D S E P L Y N M V
Cat Felis silvestris
Mouse Mus musculus P50427 624 66572 A526 R R P L T P E A E P R H R E V
Rat Rattus norvegicus P15589 577 62660 T518 R H P L T P E T E P R H G E I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514413 576 63289 T513 A N P L S P A T E P L F G T V
Chicken Gallus gallus Q5ZK90 535 61383 T480 N Y P K V S S T V Q N Y N K K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q08CJ7 523 59480 V468 S I V D Y P S V S K S V H R Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P50473 567 62459 G496 N Y P L G P C G Y E H V L L H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.7 61.3 74.1 N.A. 47.1 48 N.A. 70.3 20.9 N.A. 22.7 N.A. N.A. N.A. N.A. 27.9
Protein Similarity: 100 71.8 71.8 81.2 N.A. 57.3 59.3 N.A. 79.7 36.9 N.A. 38.2 N.A. N.A. N.A. N.A. 42.1
P-Site Identity: 100 6.6 46.6 80 N.A. 53.3 40 N.A. 53.3 13.3 N.A. 13.3 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 20 66.6 93.3 N.A. 73.3 66.6 N.A. 73.3 26.6 N.A. 20 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 30 0 0 0 0 0 20 10 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 10 20 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 20 10 60 10 0 0 0 20 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 20 0 0 0 % F
% Gly: 0 0 0 0 10 0 0 10 0 0 0 0 20 0 0 % G
% His: 0 20 0 0 0 0 0 0 0 0 10 20 20 0 10 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 20 % I
% Lys: 0 0 0 10 0 0 0 0 0 10 0 0 0 10 10 % K
% Leu: 10 0 10 70 0 0 0 0 0 10 40 0 10 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 20 10 0 10 0 0 10 0 0 0 10 0 20 0 0 % N
% Pro: 0 10 70 0 10 80 0 0 10 60 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % Q
% Arg: 20 30 0 0 0 0 0 0 0 0 20 0 10 10 0 % R
% Ser: 10 0 0 0 20 10 20 30 10 0 10 0 10 0 0 % S
% Thr: 10 0 0 0 40 0 0 30 0 0 0 0 0 10 0 % T
% Val: 0 0 20 0 10 0 0 10 10 0 10 20 0 10 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 20 0 0 10 0 0 0 10 0 0 30 10 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _