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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARSD All Species: 14.24
Human Site: T554 Identified Species: 34.81
UniProt: P51689 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51689 NP_001660.2 593 64860 T554 A V S E H R Q T L S P V P Q Q
Chimpanzee Pan troglodytes XP_520911 562 63294 L521 I R E H R R T L T P V P Q Q F
Rhesus Macaque Macaca mulatta XP_001116129 589 65549 T551 A V R E H Q R T L S P V P L Q
Dog Lupus familis XP_548838 639 70828 T599 A V E Q H R K T L S P V P T Q
Cat Felis silvestris
Mouse Mus musculus P50427 624 66572 R547 A A R A H R A R L R P A P D Q
Rat Rattus norvegicus P15589 577 62660 T539 A A R A H V A T L E E A P N Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514413 576 63289 T534 A V E A H R R T I T P V P Q Q
Chicken Gallus gallus Q5ZK90 535 61383 S501 Q S L G Q N Y S N V I A N L R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q08CJ7 523 59480 D489 E W K Q S L G D S Y S Q V I A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P50473 567 62459 I517 R H D A E M V I G T P V L D N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.7 61.3 74.1 N.A. 47.1 48 N.A. 70.3 20.9 N.A. 22.7 N.A. N.A. N.A. N.A. 27.9
Protein Similarity: 100 71.8 71.8 81.2 N.A. 57.3 59.3 N.A. 79.7 36.9 N.A. 38.2 N.A. N.A. N.A. N.A. 42.1
P-Site Identity: 100 13.3 73.3 73.3 N.A. 46.6 40 N.A. 66.6 0 N.A. 0 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 13.3 86.6 86.6 N.A. 46.6 40 N.A. 86.6 13.3 N.A. 6.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 60 20 0 40 0 0 20 0 0 0 0 30 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 10 0 0 0 0 0 20 0 % D
% Glu: 10 0 30 20 10 0 0 0 0 10 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 0 0 10 0 0 10 0 10 0 0 0 0 0 0 % G
% His: 0 10 0 10 60 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 10 10 0 10 0 0 10 0 % I
% Lys: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 0 0 10 0 10 50 0 0 0 10 20 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 10 0 0 0 10 10 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 10 60 10 60 0 0 % P
% Gln: 10 0 0 20 10 10 10 0 0 0 0 10 10 30 60 % Q
% Arg: 10 10 30 0 10 50 20 10 0 10 0 0 0 0 10 % R
% Ser: 0 10 10 0 10 0 0 10 10 30 10 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 10 50 10 20 0 0 0 10 0 % T
% Val: 0 40 0 0 0 10 10 0 0 10 10 50 10 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _