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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARSD All Species: 5.15
Human Site: Y172 Identified Species: 12.59
UniProt: P51689 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51689 NP_001660.2 593 64860 Y172 P L N H G F D Y F Y G M P F T
Chimpanzee Pan troglodytes XP_520911 562 63294 S170 L R I K L W I S T V A L A L V
Rhesus Macaque Macaca mulatta XP_001116129 589 65549 H169 P L H H G F D H F Y G M P F S
Dog Lupus familis XP_548838 639 70828 Y217 P L N H G F D Y F Y G M P F T
Cat Felis silvestris
Mouse Mus musculus P50427 624 66572 P171 F D R F L G V P T T N L R D C
Rat Rattus norvegicus P15589 577 62660 V176 C K P G G G T V F G S A Q Q V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514413 576 63289 M172 Q I G K P P H M D A A F R A K
Chicken Gallus gallus Q5ZK90 535 61383 L164 E G R P K V N L T G D R R H V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q08CJ7 523 59480 G152 P F L L R Q E G R P V T D L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P50473 567 62459 H173 T G M V G K W H L G I N E N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.7 61.3 74.1 N.A. 47.1 48 N.A. 70.3 20.9 N.A. 22.7 N.A. N.A. N.A. N.A. 27.9
Protein Similarity: 100 71.8 71.8 81.2 N.A. 57.3 59.3 N.A. 79.7 36.9 N.A. 38.2 N.A. N.A. N.A. N.A. 42.1
P-Site Identity: 100 0 80 100 N.A. 0 13.3 N.A. 0 0 N.A. 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 13.3 100 100 N.A. 6.6 13.3 N.A. 6.6 6.6 N.A. 13.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 10 20 10 10 10 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 10 0 0 0 0 30 0 10 0 10 0 10 10 0 % D
% Glu: 10 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % E
% Phe: 10 10 0 10 0 30 0 0 40 0 0 10 0 30 0 % F
% Gly: 0 20 10 10 50 20 0 10 0 30 30 0 0 0 0 % G
% His: 0 0 10 30 0 0 10 20 0 0 0 0 0 10 0 % H
% Ile: 0 10 10 0 0 0 10 0 0 0 10 0 0 0 0 % I
% Lys: 0 10 0 20 10 10 0 0 0 0 0 0 0 0 10 % K
% Leu: 10 30 10 10 20 0 0 10 10 0 0 20 0 20 0 % L
% Met: 0 0 10 0 0 0 0 10 0 0 0 30 0 0 0 % M
% Asn: 0 0 20 0 0 0 10 0 0 0 10 10 0 10 0 % N
% Pro: 40 0 10 10 10 10 0 10 0 10 0 0 30 0 0 % P
% Gln: 10 0 0 0 0 10 0 0 0 0 0 0 10 10 0 % Q
% Arg: 0 10 20 0 10 0 0 0 10 0 0 10 30 0 0 % R
% Ser: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 20 % S
% Thr: 10 0 0 0 0 0 10 0 30 10 0 10 0 0 20 % T
% Val: 0 0 0 10 0 10 10 10 0 10 10 0 0 0 40 % V
% Trp: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 20 0 30 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _