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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARSD All Species: 12.73
Human Site: Y322 Identified Species: 31.11
UniProt: P51689 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51689 NP_001660.2 593 64860 Y322 G K S Q H G L Y G D N V E E M
Chimpanzee Pan troglodytes XP_520911 562 63294 N314 L D Q E R L A N H T L V Y F T
Rhesus Macaque Macaca mulatta XP_001116129 589 65549 Y319 G K S L H G L Y G D N V E E M
Dog Lupus familis XP_548838 639 70828 Y367 G K S Q H G L Y G D N V E E M
Cat Felis silvestris
Mouse Mus musculus P50427 624 66572 Y316 G R S L H G A Y G D S V E E M
Rat Rattus norvegicus P15589 577 62660 W316 D A V E E M D W A V G Q V L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514413 576 63289 L312 S V E E M D W L I G E I L A T
Chicken Gallus gallus Q5ZK90 535 61383 L304 A L Q D T D L L K K T I I M F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q08CJ7 523 59480 L292 L G E V M A A L R D T G S L N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P50473 567 62459 V317 N D I D D N T V I F F T S D H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.7 61.3 74.1 N.A. 47.1 48 N.A. 70.3 20.9 N.A. 22.7 N.A. N.A. N.A. N.A. 27.9
Protein Similarity: 100 71.8 71.8 81.2 N.A. 57.3 59.3 N.A. 79.7 36.9 N.A. 38.2 N.A. N.A. N.A. N.A. 42.1
P-Site Identity: 100 6.6 93.3 100 N.A. 73.3 0 N.A. 0 6.6 N.A. 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 13.3 93.3 100 N.A. 86.6 13.3 N.A. 13.3 13.3 N.A. 6.6 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 10 30 0 10 0 0 0 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 20 0 20 10 20 10 0 0 50 0 0 0 10 0 % D
% Glu: 0 0 20 30 10 0 0 0 0 0 10 0 40 40 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 10 0 0 10 10 % F
% Gly: 40 10 0 0 0 40 0 0 40 10 10 10 0 0 0 % G
% His: 0 0 0 0 40 0 0 0 10 0 0 0 0 0 10 % H
% Ile: 0 0 10 0 0 0 0 0 20 0 0 20 10 0 0 % I
% Lys: 0 30 0 0 0 0 0 0 10 10 0 0 0 0 0 % K
% Leu: 20 10 0 20 0 10 40 30 0 0 10 0 10 20 0 % L
% Met: 0 0 0 0 20 10 0 0 0 0 0 0 0 10 40 % M
% Asn: 10 0 0 0 0 10 0 10 0 0 30 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 20 20 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 10 0 0 10 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 10 0 40 0 0 0 0 0 0 0 10 0 20 0 0 % S
% Thr: 0 0 0 0 10 0 10 0 0 10 20 10 0 0 20 % T
% Val: 0 10 10 10 0 0 0 10 0 10 0 50 10 0 0 % V
% Trp: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 40 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _