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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARSD
All Species:
5.15
Human Site:
Y537
Identified Species:
12.59
UniProt:
P51689
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51689
NP_001660.2
593
64860
Y537
T
P
D
S
E
P
L
Y
H
A
V
I
A
R
V
Chimpanzee
Pan troglodytes
XP_520911
562
63294
D504
P
D
N
E
P
L
L
D
S
V
I
K
K
M
E
Rhesus Macaque
Macaca mulatta
XP_001116129
589
65549
F534
T
P
A
S
E
P
V
F
Y
Q
V
M
E
R
V
Dog
Lupus familis
XP_548838
639
70828
Y582
S
P
D
S
E
P
L
Y
N
M
V
V
A
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
P50427
624
66572
H530
T
P
E
A
E
P
R
H
R
E
V
L
D
A
I
Rat
Rattus norvegicus
P15589
577
62660
H522
T
P
E
T
E
P
R
H
G
E
I
L
R
N
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514413
576
63289
F517
S
P
A
T
E
P
L
F
G
T
V
L
E
R
V
Chicken
Gallus gallus
Q5ZK90
535
61383
Y484
V
S
S
T
V
Q
N
Y
N
K
K
Q
F
I
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q08CJ7
523
59480
V472
Y
P
S
V
S
K
S
V
H
R
Y
N
K
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P50473
567
62459
V500
G
P
C
G
Y
E
H
V
L
L
H
V
K
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
61.3
74.1
N.A.
47.1
48
N.A.
70.3
20.9
N.A.
22.7
N.A.
N.A.
N.A.
N.A.
27.9
Protein Similarity:
100
71.8
71.8
81.2
N.A.
57.3
59.3
N.A.
79.7
36.9
N.A.
38.2
N.A.
N.A.
N.A.
N.A.
42.1
P-Site Identity:
100
6.6
53.3
66.6
N.A.
33.3
26.6
N.A.
46.6
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
80
93.3
N.A.
66.6
66.6
N.A.
73.3
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
10
0
0
0
0
0
10
0
0
20
10
10
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
20
0
0
0
0
10
0
0
0
0
10
10
0
% D
% Glu:
0
0
20
10
60
10
0
0
0
20
0
0
20
0
10
% E
% Phe:
0
0
0
0
0
0
0
20
0
0
0
0
10
0
0
% F
% Gly:
10
0
0
10
0
0
0
0
20
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
20
20
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
20
10
0
10
10
% I
% Lys:
0
0
0
0
0
10
0
0
0
10
10
10
30
0
0
% K
% Leu:
0
0
0
0
0
10
40
0
10
10
0
30
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
10
0
10
10
% M
% Asn:
0
0
10
0
0
0
10
0
20
0
0
10
0
10
0
% N
% Pro:
10
80
0
0
10
60
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
10
0
10
0
20
10
% Q
% Arg:
0
0
0
0
0
0
20
0
10
10
0
0
10
30
0
% R
% Ser:
20
10
20
30
10
0
10
0
10
0
0
0
0
0
10
% S
% Thr:
40
0
0
30
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
10
0
0
10
10
0
10
20
0
10
50
20
0
0
40
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
10
0
0
30
10
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _