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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARSE All Species: 13.94
Human Site: T127 Identified Species: 34.07
UniProt: P51690 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51690 NP_000038.2 589 65669 T127 G G L P T N E T T F A K I L K
Chimpanzee Pan troglodytes XP_520911 562 63294 N126 G L S C A S R N D Q C Y H P L
Rhesus Macaque Macaca mulatta XP_001116129 589 65549 T127 G G L P T N E T T F A K I L K
Dog Lupus familis XP_548838 639 70828 T175 G G L P E N E T T F A R I L Q
Cat Felis silvestris
Mouse Mus musculus P50427 624 66572 V124 G G L P P S E V T M A R L L K
Rat Rattus norvegicus P15589 577 62660 G125 A K L L K G Q G Y T T G L V G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514429 613 67318 T147 G G L P A N E T T F G E I L Q
Chicken Gallus gallus Q5ZK90 535 61383 Y122 D L M Q K H G Y Y T Q K Y G K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q08CJ7 523 59480 N135 S G H H S V S N R V E A W T R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P50473 567 62459 A156 P L Y E V T I A E A M K G A G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.5 94.7 57.2 N.A. 46.6 51 N.A. 64.9 21 N.A. 21.3 N.A. N.A. N.A. N.A. 25.6
Protein Similarity: 100 68.4 96.9 70.5 N.A. 59.7 64.8 N.A. 76.8 36.6 N.A. 37 N.A. N.A. N.A. N.A. 41.7
P-Site Identity: 100 6.6 100 80 N.A. 60 6.6 N.A. 73.3 13.3 N.A. 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 13.3 100 93.3 N.A. 80 26.6 N.A. 86.6 26.6 N.A. 20 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 20 0 0 10 0 10 40 10 0 10 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 0 10 10 0 50 0 10 0 10 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 40 0 0 0 0 0 % F
% Gly: 60 60 0 0 0 10 10 10 0 0 10 10 10 10 20 % G
% His: 0 0 10 10 0 10 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 0 0 40 0 0 % I
% Lys: 0 10 0 0 20 0 0 0 0 0 0 40 0 0 40 % K
% Leu: 0 30 60 10 0 0 0 0 0 0 0 0 20 50 10 % L
% Met: 0 0 10 0 0 0 0 0 0 10 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 40 0 20 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 50 10 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 10 0 0 10 0 0 10 10 0 0 0 20 % Q
% Arg: 0 0 0 0 0 0 10 0 10 0 0 20 0 0 10 % R
% Ser: 10 0 10 0 10 20 10 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 20 10 0 40 50 20 10 0 0 10 0 % T
% Val: 0 0 0 0 10 10 0 10 0 10 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 10 0 0 0 0 10 20 0 0 10 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _