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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARSE All Species: 6.06
Human Site: T523 Identified Species: 14.81
UniProt: P51690 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51690 NP_000038.2 589 65669 T523 L S R D P S E T H I L T P A S
Chimpanzee Pan troglodytes XP_520911 562 63294 A492 I S R D P S E A L P L N P D N
Rhesus Macaque Macaca mulatta XP_001116129 589 65549 T523 L S R D P S E T H V L T P A S
Dog Lupus familis XP_548838 639 70828 A571 L S R D P S E A R P L S P D S
Cat Felis silvestris
Mouse Mus musculus P50427 624 66572 R519 L T R D P G E R R P L T P E A
Rat Rattus norvegicus P15589 577 62660 R511 I A R D P R E R H P L T P E T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514429 613 67318 A543 L S S D P S E A N P L S P D T
Chicken Gallus gallus Q5ZK90 535 61383 S478 I V N Y P K V S S T V Q N Y N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q08CJ7 523 59480 K484 K Q Q F L E W K Q S L G D S Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P50473 567 62459 M515 I A R H D A E M V I G T P V L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.5 94.7 57.2 N.A. 46.6 51 N.A. 64.9 21 N.A. 21.3 N.A. N.A. N.A. N.A. 25.6
Protein Similarity: 100 68.4 96.9 70.5 N.A. 59.7 64.8 N.A. 76.8 36.6 N.A. 37 N.A. N.A. N.A. N.A. 41.7
P-Site Identity: 100 53.3 93.3 66.6 N.A. 53.3 53.3 N.A. 53.3 6.6 N.A. 6.6 N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: 100 66.6 100 73.3 N.A. 66.6 73.3 N.A. 73.3 33.3 N.A. 20 N.A. N.A. N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 0 0 0 10 0 30 0 0 0 0 0 20 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 70 10 0 0 0 0 0 0 0 10 30 0 % D
% Glu: 0 0 0 0 0 10 80 0 0 0 0 0 0 20 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 10 10 0 0 0 % G
% His: 0 0 0 10 0 0 0 0 30 0 0 0 0 0 0 % H
% Ile: 40 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % K
% Leu: 50 0 0 0 10 0 0 0 10 0 80 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 10 0 0 10 10 0 20 % N
% Pro: 0 0 0 0 80 0 0 0 0 50 0 0 80 0 0 % P
% Gln: 0 10 10 0 0 0 0 0 10 0 0 10 0 0 0 % Q
% Arg: 0 0 70 0 0 10 0 20 20 0 0 0 0 0 0 % R
% Ser: 0 50 10 0 0 50 0 10 10 10 0 20 0 10 30 % S
% Thr: 0 10 0 0 0 0 0 20 0 10 0 50 0 0 20 % T
% Val: 0 10 0 0 0 0 10 0 10 10 10 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _