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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARSE All Species: 20.61
Human Site: T77 Identified Species: 50.37
UniProt: P51690 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51690 NP_000038.2 589 65669 T77 A E D G V K L T Q H I S A A S
Chimpanzee Pan troglodytes XP_520911 562 63294 P76 I R S G M V S P Y N L N R A F
Rhesus Macaque Macaca mulatta XP_001116129 589 65549 T77 A E D G V K L T Q H I S A A S
Dog Lupus familis XP_548838 639 70828 T125 A E E G V R L T Q H L A A A P
Cat Felis silvestris
Mouse Mus musculus P50427 624 66572 T74 A R E G V K L T Q H L A A A P
Rat Rattus norvegicus P15589 577 62660 T75 L A A A P L C T P S R A A F L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514429 613 67318 T97 A Q E G V R L T Q H I S A A S
Chicken Gallus gallus Q5ZK90 535 61383 L72 K R H G S V F L N A Y T N S P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q08CJ7 523 59480 G85 S R A A M W S G Q F V H L T Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P50473 567 62459 T106 A N Q G L R F T Q G Y S G D S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.5 94.7 57.2 N.A. 46.6 51 N.A. 64.9 21 N.A. 21.3 N.A. N.A. N.A. N.A. 25.6
Protein Similarity: 100 68.4 96.9 70.5 N.A. 59.7 64.8 N.A. 76.8 36.6 N.A. 37 N.A. N.A. N.A. N.A. 41.7
P-Site Identity: 100 13.3 100 66.6 N.A. 66.6 13.3 N.A. 80 6.6 N.A. 6.6 N.A. N.A. N.A. N.A. 40
P-Site Similarity: 100 40 100 93.3 N.A. 86.6 20 N.A. 100 20 N.A. 26.6 N.A. N.A. N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 60 10 20 20 0 0 0 0 0 10 0 30 60 60 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 20 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 30 30 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 20 0 0 10 0 0 0 10 10 % F
% Gly: 0 0 0 80 0 0 0 10 0 10 0 0 10 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 50 0 10 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 30 0 0 0 0 % I
% Lys: 10 0 0 0 0 30 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 0 10 10 50 10 0 0 30 0 10 0 10 % L
% Met: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 10 10 0 10 10 0 0 % N
% Pro: 0 0 0 0 10 0 0 10 10 0 0 0 0 0 30 % P
% Gln: 0 10 10 0 0 0 0 0 70 0 0 0 0 0 10 % Q
% Arg: 0 40 0 0 0 30 0 0 0 0 10 0 10 0 0 % R
% Ser: 10 0 10 0 10 0 20 0 0 10 0 40 0 10 40 % S
% Thr: 0 0 0 0 0 0 0 70 0 0 0 10 0 10 0 % T
% Val: 0 0 0 0 50 20 0 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 20 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _