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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARSE All Species: 6.36
Human Site: Y367 Identified Species: 15.56
UniProt: P51690 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51690 NP_000038.2 589 65669 Y367 N Q L G N T Q Y G G W N G I Y
Chimpanzee Pan troglodytes XP_520911 562 63294 G356 G M G G W E G G I R V P G I F
Rhesus Macaque Macaca mulatta XP_001116129 589 65549 Y367 N Q L G R T Q Y G G W N G I Y
Dog Lupus familis XP_548838 639 70828 L415 A R D E R G Q L G G W N G I F
Cat Felis silvestris
Mouse Mus musculus P50427 624 66572 R364 E L G P R G E R M G G S N G V
Rat Rattus norvegicus P15589 577 62660 R355 E L G P N G E R H G G S N G I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514429 613 67318 R387 S R E G N D Q R G G W N G I Y
Chicken Gallus gallus Q5ZK90 535 61383 V359 V S A V V S L V D I Y P T M L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q08CJ7 523 59480 T368 D L A G V P Q T G G L S G H S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P50473 567 62459 P391 N L G G S Q L P T D R I Y D G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.5 94.7 57.2 N.A. 46.6 51 N.A. 64.9 21 N.A. 21.3 N.A. N.A. N.A. N.A. 25.6
Protein Similarity: 100 68.4 96.9 70.5 N.A. 59.7 64.8 N.A. 76.8 36.6 N.A. 37 N.A. N.A. N.A. N.A. 41.7
P-Site Identity: 100 20 93.3 46.6 N.A. 6.6 13.3 N.A. 66.6 0 N.A. 33.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 26.6 93.3 60 N.A. 20 26.6 N.A. 80 20 N.A. 46.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 0 0 10 0 0 10 10 0 0 0 10 0 % D
% Glu: 20 0 10 10 0 10 20 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % F
% Gly: 10 0 40 60 0 30 10 10 50 70 20 0 60 20 10 % G
% His: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 10 0 10 0 50 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 40 20 0 0 0 20 10 0 0 10 0 0 0 10 % L
% Met: 0 10 0 0 0 0 0 0 10 0 0 0 0 10 0 % M
% Asn: 30 0 0 0 30 0 0 0 0 0 0 40 20 0 0 % N
% Pro: 0 0 0 20 0 10 0 10 0 0 0 20 0 0 0 % P
% Gln: 0 20 0 0 0 10 50 0 0 0 0 0 0 0 0 % Q
% Arg: 0 20 0 0 30 0 0 30 0 10 10 0 0 0 0 % R
% Ser: 10 10 0 0 10 10 0 0 0 0 0 30 0 0 10 % S
% Thr: 0 0 0 0 0 20 0 10 10 0 0 0 10 0 0 % T
% Val: 10 0 0 10 20 0 0 10 0 0 10 0 0 0 10 % V
% Trp: 0 0 0 0 10 0 0 0 0 0 40 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 20 0 0 10 0 10 0 30 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _