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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARSE
All Species:
17.27
Human Site:
Y493
Identified Species:
42.22
UniProt:
P51690
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51690
NP_000038.2
589
65669
Y493
P
E
G
A
G
A
C
Y
G
R
K
V
C
P
C
Chimpanzee
Pan troglodytes
XP_520911
562
63294
Y463
P
E
G
T
G
A
C
Y
G
S
G
I
C
S
W
Rhesus Macaque
Macaca mulatta
XP_001116129
589
65549
Y493
P
E
G
A
G
A
C
Y
G
R
K
V
C
P
C
Dog
Lupus familis
XP_548838
639
70828
Y541
P
K
G
A
G
A
C
Y
G
R
G
V
C
P
C
Cat
Felis silvestris
Mouse
Mus musculus
P50427
624
66572
F488
P
A
G
A
N
G
C
F
S
T
H
V
C
L
C
Rat
Rattus norvegicus
P15589
577
62660
F481
P
P
G
S
N
G
C
F
S
T
H
V
C
M
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514429
613
67318
Y513
P
K
G
A
G
A
C
Y
G
R
L
V
C
P
C
Chicken
Gallus gallus
Q5ZK90
535
61383
K456
E
L
T
N
V
A
I
K
F
P
E
T
V
Q
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q08CJ7
523
59480
V463
D
K
L
L
R
S
I
V
D
Y
P
S
V
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P50473
567
62459
Y490
E
K
D
P
G
E
N
Y
P
L
G
P
C
G
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.5
94.7
57.2
N.A.
46.6
51
N.A.
64.9
21
N.A.
21.3
N.A.
N.A.
N.A.
N.A.
25.6
Protein Similarity:
100
68.4
96.9
70.5
N.A.
59.7
64.8
N.A.
76.8
36.6
N.A.
37
N.A.
N.A.
N.A.
N.A.
41.7
P-Site Identity:
100
60
100
86.6
N.A.
46.6
40
N.A.
86.6
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
66.6
100
93.3
N.A.
53.3
53.3
N.A.
93.3
13.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
50
0
60
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
70
0
0
0
0
0
80
0
60
% C
% Asp:
10
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
20
30
0
0
0
10
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
20
10
0
0
0
0
0
0
% F
% Gly:
0
0
70
0
60
20
0
0
50
0
30
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
20
0
0
0
0
10
0
0
0
% I
% Lys:
0
40
0
0
0
0
0
10
0
0
20
0
0
0
10
% K
% Leu:
0
10
10
10
0
0
0
0
0
10
10
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
10
20
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
70
10
0
10
0
0
0
0
10
10
10
10
0
40
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
40
0
0
0
0
0
% R
% Ser:
0
0
0
10
0
10
0
0
20
10
0
10
0
20
10
% S
% Thr:
0
0
10
10
0
0
0
0
0
20
0
10
0
0
0
% T
% Val:
0
0
0
0
10
0
0
10
0
0
0
60
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
60
0
10
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _